ENSMUSG00000042189


Mus musculus

Features
Gene ID: ENSMUSG00000042189
  
Biological name :Tekt3
  
Synonyms : Q6X6Z7 / Tekt3 / tektin 3
  
Possible biological names infered from orthology : Q9BXF9
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 63061654
Gene end: 63094964
  
Corresponding Affymetrix probe sets: 10376941 (MoGene1.0st)   1429143_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042063
NCBI entrez gene - 71062     See in Manteia.
MGI - MGI:1918312
RefSeq - NM_027660
RefSeq Peptide - NP_081936
swissprot - Q5SXS5
swissprot - Q6X6Z7
Ensembl - ENSMUSG00000042189
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tekt3ENSDARG00000045038Danio rerio
 TEKT3ENSGALG00000001348Gallus gallus
 TEKT3ENSG00000125409Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tekt5 / G5E8A8 / Tektin-5 / Q96M29*ENSMUSG0000003917949
Tekt4 / Q8WW24* / tektin 4*ENSMUSG0000002417535
Tekt1 / Q9DAJ2 / Tektin-1 / Q969V4*ENSMUSG0000002079930
Tekt2 / Q922G7 / Mus musculus tektin 2 (Tekt2), transcript variant 2, mRNA. / Q9UIF3* / tektin 2*ENSMUSG0000002884525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000435  Tektin
 IPR029012  Helix hairpin bin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030317 flagellated sperm motility IMP
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0060294 cilium movement involved in cell motility IBA
 biological_processGO:0060378 regulation of brood size IGI
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0036126 sperm flagellum IBA
 cellular_componentGO:0042995 cell projection IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Foxb1tm1Sli/Foxb1tm1Sli
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxb1tm1Sli/Foxb1tm1Sli
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Tekt3tm1Zuk/Tekt3tm1Zuk,Tekt4tm1Zuk/Tekt4tm1Zuk
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0009243 hairpin sperm flagellum "a structural alteration where the sperm flagellum becomes bent back (folded) on itself to form a hairpin (loop) structure; a sharp hairpin-like bend formation can disrupt the axial structures and cause the sperm tail to become kinked" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Foxb1tm1Sli/Foxb1tm1Sli
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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