ENSMUSG00000042622


Mus musculus

Features
Gene ID: ENSMUSG00000042622
  
Biological name :Maff
  
Synonyms : Maff / O54791 / Transcription factor MafF
  
Possible biological names infered from orthology : MAF bZIP transcription factor F / Q9ULX9
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 79346621
Gene end: 79359076
  
Corresponding Affymetrix probe sets: 10425283 (MoGene1.0st)   1418936_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000094076
Ensembl peptide - ENSMUSP00000131628
Ensembl peptide - ENSMUSP00000154850
Ensembl peptide - ENSMUSP00000155516
NCBI entrez gene - 17133     See in Manteia.
MGI - MGI:96910
RefSeq - XM_011245484
RefSeq - NM_001304830
RefSeq - NM_001304831
RefSeq - NM_001304832
RefSeq - NM_010755
RefSeq - XM_006520546
RefSeq - XM_006520550
RefSeq Peptide - NP_034885
RefSeq Peptide - NP_001291759
RefSeq Peptide - NP_001291760
RefSeq Peptide - NP_001291761
swissprot - O54791
swissprot - Q3U0G5
Ensembl - ENSMUSG00000042622
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 maffENSDARG00000028957Danio rerio
 MAFFENSGALG00000012277Gallus gallus
 MAFFENSG00000185022Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mafk / Q61827 / v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) / O60675* / MAF bZIP transcription factor K*ENSMUSG0000001814365
Mafg / O54790 / Transcription factor MafG / O15525* / MAF bZIP transcription factor G*ENSMUSG0000005151063
Maf / P54843 / Transcription factor Maf / O75444* / MAF bZIP transcription factor*ENSMUSG0000005543542
Mafb / P54841 / Transcription factor MafB / Q9Y5Q3* / MAF bZIP transcription factor B*ENSMUSG0000007462241
Mafa / Q8CF90 / Transcription factor MafA / Q8NHW3* / MAF bZIP transcription factor A*ENSMUSG0000004759140
Nrl / P54846 / Neural retina-specific leucine zipper protein / P54845* / neural retina leucine zipper*ENSMUSG0000004063236


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR024874  Transcription factor Maf family
 IPR033531  Transcription factor MafF


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IMP
 biological_processGO:0045604 regulation of epidermal cell differentiation IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005739 mitochondrion ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding ISO


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pdgfratm9(Pdgfra/Fgfr1)Sor/Pdgfra+
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Mafftm1.1Jeng/Mafftm1.1Jeng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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