ENSMUSG00000042750


Mus musculus

Features
Gene ID: ENSMUSG00000042750
  
Biological name :Bex2
  
Synonyms : Bex2 / Protein BEX2 / Q9WTZ8
  
Possible biological names infered from orthology : BEX1 / brain expressed X-linked 1 / brain expressed X-linked 2 / Q9BXY8 / Q9HBH7
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F1
Gene start: 136066564
Gene end: 136068236
  
Corresponding Affymetrix probe sets: 10606835 (MoGene1.0st)   1417388_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043113
NCBI entrez gene - 12069     See in Manteia.
MGI - MGI:1338017
RefSeq - NM_009749
RefSeq Peptide - NP_033879
swissprot - Q9WTZ8
Ensembl - ENSMUSG00000042750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BEX1ENSG00000133169Homo sapiens
 BEX2ENSG00000133134Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bex1 / Q9R224 / Protein BEX1 / BEX2* / Q9BXY8* / Q9HBH7* / brain expressed X-linked 1* / brain expressed X-linked 2*ENSMUSG0000005007186


Protein motifs (from Interpro)
Interpro ID Name
 IPR007623  Brain-expressed X-linked protein
 IPR021156  Transcription elongation factor A-like/Brain expressed X-linked


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005667 transcription factor complex ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000218 increased WBC count "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0001488 increased startle reflex "reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

 MP:0002968 increased circulating alkaline phosphatase level "elevated activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Barx2tm1b(EUCOMM)Hmgu/Barx2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Barx2tm1b(EUCOMM)Hmgu/H

Allelic Composition: Bex2tm1b(EUCOMM)Hmgu/Bex2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Bex2tm1b(EUCOMM)Hmgu/Ieg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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