ENSMUSG00000042873


Mus musculus
componentmembranepostsynapticLhfpl4lipomahmgicfusionpartner-likeproteinbiologicalprocesscellularintegralmolecularfunctionminiatureinhibitorycurrentsdensity

Features
Gene ID: ENSMUSG00000042873
  
Biological name :Lhfpl4
  
Synonyms : Lhfpl4 / LHFPL tetraspan subfamily member 4 protein / Q5U4E0
  
Possible biological names infered from orthology : LHFPL tetraspan subfamily member 4 / Q7Z7J7
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: E3
Gene start: 113168090
Gene end: 113195384
  
Corresponding Affymetrix probe sets: 10546884 (MoGene1.0st)   1436553_at (Mouse Genome 430 2.0 Array)   1442043_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000144899
Ensembl peptide - ENSMUSP00000124470
NCBI entrez gene - 269788     See in Manteia.
MGI - MGI:3057108
RefSeq - NM_177763
RefSeq - XM_017321600
RefSeq Peptide - NP_808431
swissprot - A0A0N4SV06
swissprot - Q5U4E0
Ensembl - ENSMUSG00000042873
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lhfpl4aENSDARG00000111810Danio rerio
 LHFPL4ENSGALG00000037636Gallus gallus
 LHFPL4ENSG00000156959Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lhfpl3 / LHFPL tetraspan subfamily member 3 protein isoform 1 / Q86UP9* / LHFPL tetraspan subfamily member 3*ENSMUSG0000010637968
Lhfpl5 / Q4KL25 / LHFPL tetraspan subfamily member 5 protein / Q8TAF8* / LHFPL tetraspan subfamily member 5*ENSMUSG0000006225253
Lhfpl2 / Q8BGA2 / LHFPL tetraspan subfamily member 2 protein / Q6ZUX7* / LHFPL tetraspan subfamily member 2*ENSMUSG0000004531221
Lhfp / Q8BM86 / LHFPL tetraspan subfamily member 6 protein / Q9Y693* / LHFPL6* / LHFPL tetraspan subfamily member 6*ENSMUSG0000004833221
Lhfpl1 / Q80SV1 / LHFPL tetraspan subfamily member 1 protein / Q86WI0* / LHFPL tetraspan subfamily member 1*ENSMUSG0000004170017


Protein motifs (from Interpro)
Interpro ID Name
 IPR019372  Lipoma HMGIC fusion partner-like protein


Gene Ontology (GO)
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
nervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotypenervous system phenotype
IDPhenotypeDefinition Genetic BG
 MP:0009435 abnormal miniature inhibitory postsynaptic currents "defect in the size or duration of spontaneous currents detected in postsynaptic cells that occur in the absence of an inhibitory impulse" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

 MP:0020551 abnormal postsynaptic density morphology "any structural anomaly of the electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymetric, neuron-neuron synapse" [GO:0014069]
Show

Allelic Composition: Hmcesem2Dfel/Hmces+
Genetic Background: involves: 129 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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