ENSMUSG00000042961


Mus musculus

Features
Gene ID: ENSMUSG00000042961
  
Biological name :Egflam
  
Synonyms : Egflam / Pikachurin / Q4VBE4
  
Possible biological names infered from orthology : EGF like, fibronectin type III and laminin G domains / Q63HQ2
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: A1
Gene start: 7206120
Gene end: 7398395
  
Corresponding Affymetrix probe sets: 10427496 (MoGene1.0st)   1434647_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055599
Ensembl peptide - ENSMUSP00000094238
Ensembl peptide - ENSMUSP00000125188
NCBI entrez gene - 268780     See in Manteia.
MGI - MGI:2146149
RefSeq - XM_017316629
RefSeq - NM_001289496
RefSeq - NM_001289498
RefSeq - NM_178748
RefSeq - XM_006519991
RefSeq - XM_017316628
RefSeq Peptide - NP_848863
RefSeq Peptide - NP_001276425
RefSeq Peptide - NP_001276427
swissprot - Q4VBE4
swissprot - E0CXM4
Ensembl - ENSMUSG00000042961
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT737133.1ENSDARG00000099008Danio rerio
 EGFLAMENSGALG00000003726Gallus gallus
 EGFLAMENSG00000164318Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hspg2 / perlecan (heparan sulfate proteoglycan 2) / P98160* / heparan sulfate proteoglycan 2*ENSMUSG0000002876329
Agrn / A2ASQ1 / Agrin Agrin N-terminal 110 kDa subunit Agrin C-terminal 110 kDa subunit Agrin C-terminal 90 kDa fragment Agrin C-terminal 22 kDa fragment / agrin* / O00468*ENSMUSG0000004193623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001791  Laminin G domain
 IPR001881  EGF-like calcium-binding domain
 IPR003961  Fibronectin type III
 IPR013032  EGF-like, conserved site
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010811 positive regulation of cell-substrate adhesion IDA
 biological_processGO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan IDA
 biological_processGO:0030198 extracellular matrix organization IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005604 basement membrane IDA
 cellular_componentGO:0005614 interstitial matrix IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005539 glycosaminoglycan binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001005 abnormal rod morphology "structural or developmental anomaly of the photoreceptors that contain rhodopsin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tal1tm1Por/Tal1tm1Por
Genetic Background: involves: 129P2/OlaHsd

 MP:0001006 abnormal cone morphology "structural or developmental anomaly of the retinal receptors that give rise to color vision" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tal1tm1Por/Tal1tm1Por
Genetic Background: involves: 129P2/OlaHsd

 MP:0004021 abnormal rod electrophysiology "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tal1tm1Por/Tal1tm1Por
Genetic Background: involves: 129P2/OlaHsd

 MP:0004022 abnormal cone electrophysiology "anomaly in the function of light adapted vision mediated by the cones" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tal1tm1Por/Tal1tm1Por
Genetic Background: involves: 129P2/OlaHsd

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tal1tm1Por/Tal1tm1Por
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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