ENSMUSG00000043366


Mus musculus

Features
Gene ID: ENSMUSG00000043366
  
Biological name :Olfr78
  
Synonyms : Olfactory receptor 51E2 / Olfr78 / Q8VBV9
  
Possible biological names infered from orthology : olfactory receptor family 51 subfamily E member 2 / OR51E2 / Q9H255
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E3
Gene start: 102738511
Gene end: 102759471
  
Corresponding Affymetrix probe sets: 10566172 (MoGene1.0st)   1421506_at (Mouse Genome 430 2.0 Array)   1421507_at (Mouse Genome 430 2.0 Array)   1440009_at (Mouse Genome 430 2.0 Array)   1453535_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058085
Ensembl peptide - ENSMUSP00000133255
Ensembl peptide - ENSMUSP00000149274
NCBI entrez gene - 170639     See in Manteia.
MGI - MGI:2157548
RefSeq - NM_001168503
RefSeq - NM_130866
RefSeq Peptide - NP_001161975
RefSeq Peptide - NP_570936
swissprot - Q8VBV9
Ensembl - ENSMUSG00000043366
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OR51E2ENSGALG00000044591Gallus gallus
 OR51E2ENSG00000167332Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Olfr557 / olfactory receptor family 51 subfamily D member 1 / OR51D1* / Q8NGF3*ENSMUSG0000007396757
Olfr558 / olfactory receptor family 51 subfamily E member 1 / OR51E1* / Q8TCB6*ENSMUSG0000007042356


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000725  Olfactory receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISA
 biological_processGO:0007608 sensory perception of smell ISS
 biological_processGO:0043401 steroid hormone mediated signaling pathway ISO
 biological_processGO:0045777 positive regulation of blood pressure IMP
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA
 biological_processGO:0071398 cellular response to fatty acid IDA
 biological_processGO:1900135 positive regulation of renin secretion into blood stream IMP
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISA
 molecular_functionGO:0003707 steroid hormone receptor activity ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004984 olfactory receptor activity ISS
 molecular_functionGO:0038023 signaling receptor activity IDA


Pathways (from Reactome)
Pathway description
Olfactory Signaling Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000819 abnormal olfactory bulb morphology "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]
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Allelic Composition: Aldh1a2tm1Gdu/Aldh1a2tm1Gdu,Aldh1a3tm1Gdu/Aldh1a3tm1Gdu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002739 abnormal olfactory bulb development "abnormality in the progression of the formation of the olfactory bulb" [J:65380, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Gsk3btm1.1Atak/Gsk3b+
Genetic Background: involves: C57BL/6

 MP:0003438 abnormal carotid body physiology "any functional change in a small epithelioid structure consisting of a small cluster of chemoreceptive and supporting cells located near the bifurcation of the common carotid artery that serves as a chemoreceptive organ that senses the pH, carbon dioxide, and oxygen concentrations in the blood and plays a crucial role in their homeostatic control" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Plin5tm1e(KOMP)Wtsi/Plin5tm1e(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0005572 abnormal breathing frequency "deviation from the normal number of breaths in a given period of time" [RGD:Rat Genome Database submission]
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Allelic Composition: Plin5tm1e(KOMP)Wtsi/Plin5tm1e(KOMP)Wtsi
Genetic Background: involves: C57BL/6N

 MP:0006092 abnormal olfactory neuron morphology "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950]
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Allelic Composition: Lhx2tm1Dra/Lhx2tm1Dra,Olfr78tm1Jgst/Olfr78+
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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