ENSMUSG00000043487


Mus musculus

Features
Gene ID: ENSMUSG00000043487
  
Biological name :Acot6
  
Synonyms : Acot6 / Acyl-coenzyme A thioesterase 6 / Q32Q92
  
Possible biological names infered from orthology : acyl-CoA thioesterase 6 / Q3I5F7
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 84100654
Gene end: 84111349
  
Corresponding Affymetrix probe sets: 10397172 (MoGene1.0st)   1428803_at (Mouse Genome 430 2.0 Array)   1460388_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152129
Ensembl peptide - ENSMUSP00000056131
NCBI entrez gene - 217700     See in Manteia.
MGI - MGI:1921287
RefSeq - NM_172580
RefSeq Peptide - NP_766168
swissprot - B2RTE4
swissprot - Q32Q92
Ensembl - ENSMUSG00000043487
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acot20ENSDARG00000042510Danio rerio
 acot21ENSDARG00000042513Danio rerio
 acot22ENSDARG00000058945Danio rerio
 ENSGALG00000009292Gallus gallus
 ACOT6ENSG00000205669Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acot5 / Q6Q2Z6 / acyl-CoA thioesterase 5 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000004254070
Acot3 / Q9QYR7 / acyl-CoA thioesterase 3 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000002122869
Acot4 / Q8BWN8 / acyl-CoA thioesterase 4 / Q8N9L9*ENSMUSG0000005239268
Acot1 / O55137 / acyl-CoA thioesterase 1 / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2*ENSMUSG0000007294967
Acot2 / Q9QYR9 / acyl-CoA thioesterase 2 / ACOT1* / P49753* / Q86TX2* / acyl-CoA thioesterase 1*ENSMUSG0000002122665
A2AKK5 / Acnat1 / acyl-coenzyme A amino acid N-acyltransferase 1ENSMUSG0000007098545
Acnat2 / Q8BGG9 / acyl-coenzyme A amino acid N-acyltransferase 2ENSMUSG0000006031744
Baat / Q91X34 / Bile acid-CoA:amino acid N-acyltransferase / Q14032*ENSMUSG0000003965342
AC133183.1 / ACOT1* / ACOT2* / Q86TX2* / P49753* / acyl-CoA thioesterase 1* / acyl-CoA thioesterase 2*ENSMUSG0000011347520


Protein motifs (from Interpro)
Interpro ID Name
 IPR006862  Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
 IPR014940  BAAT/Acyl-CoA thioester hydrolase C-terminal
 IPR016662  Acyl-CoA thioesterase, long chain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process IBA
 cellular_componentGO:0005777 peroxisome TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of very long chain fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Arhgap35m1Bchd/Arhgap35tm1Jset
Genetic Background: involves: 129S2/SvPas * C3H/HeNCrl * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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