ENSMUSG00000044921


Mus musculus

Features
Gene ID: ENSMUSG00000044921
  
Biological name :Rassf9
  
Synonyms : Q8K342 / Ras association domain-containing protein 9 / Rassf9
  
Possible biological names infered from orthology : O75901 / Ras association domain family member 9
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D1
Gene start: 102512222
Gene end: 102549736
  
Corresponding Affymetrix probe sets: 10366153 (MoGene1.0st)   1427942_at (Mouse Genome 430 2.0 Array)   1440411_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151843
Ensembl peptide - ENSMUSP00000054767
NCBI entrez gene - 237504     See in Manteia.
MGI - MGI:2384307
RefSeq - NM_146240
RefSeq - XM_006513632
RefSeq Peptide - NP_666352
swissprot - A0A1X7SB70
swissprot - Q8K342
Ensembl - ENSMUSG00000044921
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rassf9ENSDARG00000074721Danio rerio
 RASSF9ENSGALG00000027633Gallus gallus
 O75901ENSG00000198774Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BL43 / Rassf10 / Ras association domain-containing protein 10 / A6NK89* / Ras association domain family member 10*ENSMUSG0000009813237


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR033593  N-terminal RASSF family
 IPR033633  Ras association domain-containing protein 9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016197 endosomal transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0012510 trans-Golgi network transport vesicle membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: Fa2htm1.1Hama/Fa2htm1.1Hama
Genetic Background: involves: 129 * C57BL/6

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0000427 abnormal hair cycle "aberrant growth or asynchronous timing of the hair growth " [J:65302]
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Allelic Composition: Fa2htm1.1Hama/Fa2htm1.1Hama
Genetic Background: involves: 129 * C57BL/6

 MP:0001183 overexpanded alveoli "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0001219 thickened epidermis "increase in the width of the epidermal cell layer in the skin" [J:65146]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0001222 epidermal hyperplasia "increase in size of the epidermis due to increase in epidermal cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0001245 thick dermal layer "increased depth of the dermis" [J:65033]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fa2htm1.1Hama/Fa2htm1.1Hama
Genetic Background: involves: 129 * C57BL/6

 MP:0002656 abnormal keratinocyte differentiation "developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0002796 impaired skin barrier function "impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0003786 premature aging "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0003809 abnormal hair shaft morphology "irregular or unusual structure of the cuticle, and/or cortex and/or medulla of a hair" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0004971 dermal hyperplasia "overdevelopment or increased size, usually due an increased number of cells in the dermal layer of the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0005501 abnormal skin physiology "atypical function of the membranous protective covering of the body" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0008844 decreased subcutaneous adipose tissue amount "reduction in amount of adipose tissue beneath the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0008858 abnormal hair cycle anagen phase "anomaly in the growth phase of the hair cycle" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0009583 increased keratinocyte proliferation "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0010680 abnormal skin adnexa physiology "any functional anomaly of the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0010825 abnormal lung saccule morphology "any structural anomaly of the transient dilations of the developing alveolar (or transient) ducts, which transform into a transitory alveolar duct as soon as it develops further branches; the last transitory saccule formed on each pathway is a terminal saccule that develops into an alveolar sac after birth" [GO:0060430, ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Rassf9Tg(PDLIM7*)2Cml/Rassf9Tg(PDLIM7*)2Cml
Genetic Background: involves: ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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