ENSMUSG00000044976


Mus musculus

Features
Gene ID: ENSMUSG00000044976
  
Biological name :Wdr72
  
Synonyms : D3YYM4 / Wdr72 / WD repeat domain 72
  
Possible biological names infered from orthology : Q3MJ13
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: D
Gene start: 74110356
Gene end: 74283308
  
Corresponding Affymetrix probe sets: 10587051 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000149349
Ensembl peptide - ENSMUSP00000057320
NCBI entrez gene - 546144     See in Manteia.
MGI - MGI:3583957
RefSeq - XM_006511283
RefSeq - XM_006511280
RefSeq - XM_006511281
RefSeq - XM_006511282
RefSeq - NM_001033500
RefSeq - XM_006511279
RefSeq Peptide - NP_001028672
swissprot - D3YYM4
swissprot - A0A1L1SR77
Ensembl - ENSMUSG00000044976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01073424.1ENSDARG00000107858Danio rerio
 WDR72ENSGALG00000004545Gallus gallus
 WDR72ENSG00000166415Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wdr7 / Q920I9 / WD repeat domain 7 / Q9Y4E6*ENSMUSG0000004056031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011044  Quinoprotein amine dehydrogenase, beta chain-like
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0070166 enamel mineralization IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Srftm1Rmn/Srftm1Rmn,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

 MP:0002576 abnormal enamel morphology "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srftm1Rmn/Srftm1Rmn,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

 MP:0002577 reduced enamel thickness "thin hard coating of the exposed portion of the tooth" [J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srftm1Rmn/Srftm1Rmn,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

 MP:0002650 abnormal ameloblast morphology "malformation of the epithelial cells of the inner layer of the enamel organ of the developing tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Srftm1Rmn/Srftm1Rmn,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

 MP:0030450 abnormal enamel mineralization "anomaly in the process by which calcium salts, mainly carbonated hydroxyapatite, are deposited into the dental enamel" [GO:0070166]
Show

Allelic Composition: Srftm1Rmn/Srftm1Rmn,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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