ENSMUSG00000044985


Mus musculus
receptorOlfr124olfactorysensorymembraneactivityrhodopsin-likesignalg-proteincoupledperceptionsmellstimulusneurongprotein-coupledgpcrtmtransductionsignalingpathwayresponsedetectionchemicalinvolvedplasmaintegralcomponentobsoletetransducerphenotype

Features
Gene ID: ENSMUSG00000044985
  
Biological name :Olfr124
  
Synonyms : Olfr124
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 37799888
Gene end: 37808617
  
Corresponding Affymetrix probe sets: 10445158 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000150687
Ensembl peptide - ENSMUSP00000050544
Ensembl peptide - ENSMUSP00000148904
Ensembl peptide - ENSMUSP00000149754
NCBI entrez gene - 259064     See in Manteia.
MGI - MGI:2177507
RefSeq - NM_147062
RefSeq Peptide - NP_667273
swissprot - Q8VGW6
Ensembl - ENSMUSG00000044985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Olfr1360ENSMUSG0000010853465
Olfr1359ENSMUSG0000010867465
Olfr222 / olfactory receptor family 2 subfamily B member 11 / OR2B11* / Q5JQS5*ENSMUSG0000005961062
Olfr11 / Q60890 / Olfactory receptor 11 / OR2B6* / P58173* / olfactory receptor family 2 subfamily B member 6*ENSMUSG0000003665861
Olfr1370ENSMUSG0000004286959
Olfr138ENSMUSG0000005744357
Olfr133ENSMUSG0000006324057
Olfr134ENSMUSG0000009600957
Olfr136ENSMUSG0000009684057
Olfr135ENSMUSG0000005780156
Olfr1367ENSMUSG0000004550855
Olfr223ENSMUSG0000004891952


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000725  Olfactory receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
cell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcellular response to stimulussystem processresponse to chemicaldetection of stimuluscell communicationcell communicationcellular response to stimulucellular response to stimulussystem processsystem processresponse to chemicalresponse to chemicaldetection of stimulusdetection of stimulus
signaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISA
 biological_processGO:0007608 sensory perception of smell IBA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004984 olfactory receptor activity ISA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
nervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypecraniofacial phenotypetaste/olfaction phenotypegrowth/size phenotyperespiratory system phenotypenervous system phenotypenervous system phenotypecraniofacial phenotypecraniofacial phenotypetaste/olfaction phenotypetaste/olfaction phenotypegrowth/size phenotypegrowth/size phenotyperespiratory system phenotyperespiratory system phenotype
IDPhenotypeDefinition Genetic BG
 MP:0001003 abnormal olfactory receptor morphology "anomalous structure of the specialized proteins within the neurons of the olfactory epithelium that normally bind and detect odorants " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kdrtm1.1Jamb/Kdrtm1.1Jamb,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Foxo1tm1.1Stlp/Foxo1tm1.1Stlp,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S4/SvJae

 MP:0006092 abnormal olfactory neuron morphology "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950]
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Allelic Composition: Kdrtm1.1Jamb/Kdrtm1.1Jamb,Tg(KRT14-cre)1Efu/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

 MP:0011677 abnormal olfactory sensory neuron physiology "any functional anomaly of cells that innervate the olfactory epithelium and are responsible for receiving and transmitting odorant signals" [MGI:csmith]
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Allelic Composition: Arntltm1.2Shbi/Arntltm1.2Shbi
Genetic Background: involves: C57BL/6J

Allelic Composition: Olfr124tm2Mom/Olfr124+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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