ENSMUSG00000045348


Mus musculus

Features
Gene ID: ENSMUSG00000045348
  
Biological name :Nyap1
  
Synonyms : Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 / Nyap1 / Q6PFX7
  
Possible biological names infered from orthology : neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1 / Q6ZVC0
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G2
Gene start: 137729899
Gene end: 137741607
  
Corresponding Affymetrix probe sets: 10534912 (MoGene1.0st)   1439770_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058217
Ensembl peptide - ENSMUSP00000113397
Ensembl peptide - ENSMUSP00000114694
Ensembl peptide - ENSMUSP00000148318
NCBI entrez gene - 243300     See in Manteia.
MGI - MGI:2443880
RefSeq - XM_006504577
RefSeq - NM_175521
RefSeq - XM_006504575
RefSeq - XM_006504576
RefSeq Peptide - NP_001334434
RefSeq Peptide - NP_780730
swissprot - Q6PFX7
swissprot - E9PXJ0
Ensembl - ENSMUSG00000045348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR854980.1ENSDARG00000103123Danio rerio
 NYAP1ENSG00000166924Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nyap2 / neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2 / Q9P242* / neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2*ENSMUSG0000005497625


Protein motifs (from Interpro)
Interpro ID Name
 IPR026722  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1/2
 IPR026724  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1
 IPR029353  Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0048812 neuron projection morphogenesis IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0002175 low brain weight "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
Show

Allelic Composition: Gzmbtm1Ley/Gzmbtm1Ley,Serpinb9tm1.1Pib/Serpinb9tm1.1Pib
Genetic Background: involves: 129S2/SvPas * BALB/cJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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