ENSMUSG00000045731


Mus musculus

Features
Gene ID: ENSMUSG00000045731
  
Biological name :Pnoc
  
Synonyms : Pnoc / prepronociceptin / Q64387
  
Possible biological names infered from orthology : Q13519
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D1
Gene start: 65400673
Gene end: 65425472
  
Corresponding Affymetrix probe sets: 10420853 (MoGene1.0st)   1425892_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054210
Ensembl peptide - ENSMUSP00000153589
NCBI entrez gene - 18155     See in Manteia.
MGI - MGI:105308
RefSeq - XM_006518684
RefSeq - NM_001205075
RefSeq - NM_010932
RefSeq Peptide - NP_001192004
RefSeq Peptide - NP_035062
swissprot - Q543U6
swissprot - Q64387
swissprot - B7ZMX9
Ensembl - ENSMUSG00000045731
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnocaENSDARG00000025024Danio rerio
 pnocbENSDARG00000024189Danio rerio
 PNOCENSGALG00000016620Gallus gallus
 PNOCENSG00000168081Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002367  Nociceptin
 IPR006024  Opioid neuropeptide precursor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007218 neuropeptide signaling pathway IBA
 biological_processGO:0007268 chemical synaptic transmission IBA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007600 sensory perception IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0030425 dendrite IBA
 cellular_componentGO:0043025 neuronal cell body IBA
 cellular_componentGO:0043679 axon terminus IBA
 molecular_functionGO:0001515 opioid peptide activity IEA
 molecular_functionGO:0005184 neuropeptide hormone activity IBA
 molecular_functionGO:0031628 opioid receptor binding IBA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002734 abnormal mechanical nociception "abnormal capability to sense pain elicited by mechanical stimulation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fancgtm1Ada/Fancgtm1Ada
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009746 enhanced behavioral response to xenobiotic "increased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or reduced dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rdh11tm1Akjc/Rdh11tm1Akjc
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027584 Oprl1 / P35377 / opioid receptor-like 1 / P41146* / opioid related nociceptin receptor 1*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr