ENSMUSG00000046324


Mus musculus

Features
Gene ID: ENSMUSG00000046324
  
Biological name :Ermp1
  
Synonyms : Endoplasmic reticulum metallopeptidase 1 / Ermp1 / Q3UVK0
  
Possible biological names infered from orthology : Q7Z2K6
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C1
Gene start: 29608214
Gene end: 29648415
  
Corresponding Affymetrix probe sets: 10466947 (MoGene1.0st)   1433702_at (Mouse Genome 430 2.0 Array)   1446228_at (Mouse Genome 430 2.0 Array)   1460599_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057069
Ensembl peptide - ENSMUSP00000124881
Ensembl peptide - ENSMUSP00000124992
NCBI entrez gene - 226090     See in Manteia.
MGI - MGI:106250
RefSeq - XM_006526990
RefSeq - NM_001081213
RefSeq Peptide - NP_001074682
swissprot - F6TQS9
swissprot - Q3UVK0
swissprot - G8JL46
Ensembl - ENSMUSG00000046324
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01088049.1ENSDARG00000110653Danio rerio
 ERMP1ENSGALG00000000438Gallus gallus
 ERMP1ENSG00000099219Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007484  Peptidase M28


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000111 cleft palate "congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0001293 anophthalmia "congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0004158 right aortic arch "the aortic arch lies to the right of the trachea and esophagus; results from persistance of the entire right dorsal arch and involution of a segment of the left arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0005170 cleft lip "defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Dnmt3atm1b(KOMP)Wtsi/Dnmt3atm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dnmt3atm1b(KOMP)Wtsi/J

 MP:0010466 vascular ring "the trachea and esophagus are completely encircled by connected segments of the aortic arch and its branches" [http://emedicine.medscape.com]
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Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0010488 abnormal left subclavian artery morphology "any structural anomaly of the artery that extends from the aortic arch to the left side of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0011659 interrupted aortic arch, type b "complete discontinuation/blockage between the ascending and descending aorta with the interruption located between second carotid artery and ipsilateral subclavian artery" [MGI:csmith]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

 MP:0011670 double outlet right ventricle, noncommitted ventricular septal defect "a form of DORV in which the ventricular septal defect is distant from both the aorta and pulmonary artery and blood mixes in the right ventricle before entering these vessels, with the majority of deoxygenated blood entering the aorta" [MGI:csmith]
Show

Allelic Composition: Myocdtm1(cre)Dzw/Myocdtm1(cre)Dzw
Genetic Background: involves: 129 * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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