ENSMUSG00000046442


Mus musculus

Features
Gene ID: ENSMUSG00000046442
  
Biological name :Ppm1e
  
Synonyms : Ppm1e / Protein phosphatase 1E / Q80TL0
  
Possible biological names infered from orthology : protein phosphatase, Mg2+/Mn2+ dependent 1E / Q8WY54
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 87226906
Gene end: 87359023
  
Corresponding Affymetrix probe sets: 10389617 (MoGene1.0st)   1434990_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000061278
NCBI entrez gene - 320472     See in Manteia.
MGI - MGI:2444096
RefSeq - NM_177167
RefSeq Peptide - NP_796141
swissprot - B2KGP3
swissprot - Q80TL0
Ensembl - ENSMUSG00000046442
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppm1eENSDARG00000026499Danio rerio
 PPM1EENSGALG00000005061Gallus gallus
 PPM1EENSG00000175175Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppm1f / Q8CGA0 / Protein phosphatase 1F / P49593* / protein phosphatase, Mg2+/Mn2+ dependent 1F*ENSMUSG0000002618129
Ilkap / Q8R0F6 / Mus musculus integrin-linked kinase-associated serine/threonine phosphatase 2C (Ilkap), transcript variant 2, mRNA. / Q9H0C8* / ILK associated serine/threonine phosphatase*ENSMUSG0000002630914
Ppm1k / Q8BXN7 / protein phosphatase 1K (PP2C domain containing) / Q8N3J5* / protein phosphatase, Mg2+/Mn2+ dependent 1K*ENSMUSG0000003782613
Ppm1l / Q8BHN0 / Protein phosphatase 1L / Q5SGD2* / protein phosphatase, Mg2+/Mn2+ dependent 1L*ENSMUSG0000002778412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity ISO
 biological_processGO:0006470 protein dephosphorylation IMP
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation ISO
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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