ENSMUSG00000046997


Mus musculus

Features
Gene ID: ENSMUSG00000046997
  
Biological name :Spsb4
  
Synonyms : Q8R5B6 / SPRY domain-containing SOCS box protein 4 / Spsb4
  
Possible biological names infered from orthology : Q96A44 / splA/ryanodine receptor domain and SOCS box containing 4
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E3.3
Gene start: 96943482
Gene end: 97018843
  
Corresponding Affymetrix probe sets: 10595848 (MoGene1.0st)   1451418_a_at (Mouse Genome 430 2.0 Array)   1451419_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057849
NCBI entrez gene - 211949     See in Manteia.
MGI - MGI:2183445
RefSeq - NM_145134
RefSeq Peptide - NP_660116
swissprot - Q8R5B6
Ensembl - ENSMUSG00000046997
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spsb4aENSDARG00000016084Danio rerio
 SPSB4ENSGALG00000032053Gallus gallus
 SPSB4ENSG00000175093Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Spsb1 / Q9D5L7 / SPRY domain-containing SOCS box protein 1 / Q96BD6* / splA/ryanodine receptor domain and SOCS box containing 1*ENSMUSG0000003991174
Spsb2 / O88838 / SPRY domain-containing SOCS box protein 2 / Q99619* / splA/ryanodine receptor domain and SOCS box containing 2*ENSMUSG0000003845150
Fbxo45 / Q8K3B1 / F-box/SPRY domain-containing protein 1 / P0C2W1* / F-box protein 45*ENSMUSG0000003576433


Protein motifs (from Interpro)
Interpro ID Name
 IPR001496  SOCS box domain
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR036036  SOCS box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr