ENSMUSG00000047026


Mus musculus

Features
Gene ID: ENSMUSG00000047026
  
Biological name :Acsm4
  
Synonyms : Acsm4 / Acyl-coenzyme A synthetase ACSM4, mitochondrial / Q80W40
  
Possible biological names infered from orthology : acyl-CoA synthetase medium chain family member 4 / P0C7M7
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F2
Gene start: 119690026
Gene end: 119714565
  
Corresponding Affymetrix probe sets: 10556749 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000045160
NCBI entrez gene - 233801     See in Manteia.
MGI - MGI:2681844
RefSeq - NM_178414
RefSeq Peptide - NP_848501
swissprot - Q80W40
Ensembl - ENSMUSG00000047026
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ACSM4ENSG00000215009Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acsm5 / Q8BGA8 / Acyl-coenzyme A synthetase ACSM5, mitochondrial / Q6NUN0* / acyl-CoA synthetase medium chain family member 5*ENSMUSG0000003097261
Acsm3 / Q3UNX5 / Acyl-coenzyme A synthetase ACSM3, mitochondrial / Q53FZ2* / acyl-CoA synthetase medium chain family member 3*ENSMUSG0000003093559
Acsm2 / Q8K0L3 / Acyl-coenzyme A synthetase ACSM2, mitochondrial / ACSM2B* / Q68CK6* / ACSM2A* / Q08AH3* / acyl-CoA synthetase medium chain family member 2B* / acyl-CoA synthetase medium c...ENSMUSG0000003094556
Acsm1 / Q91VA0 / Acyl-coenzyme A synthetase ACSM1, mitochondrial / Q08AH1* / acyl-CoA synthetase medium chain family member 1*ENSMUSG0000003353353
Acss1 / Q99NB1 / Acetyl-coenzyme A synthetase 2-like, mitochondrial / Q9NUB1* / acyl-CoA synthetase short chain family member 1*ENSMUSG0000002745227
Acss2 / Q9QXG4 / Acetyl-coenzyme A synthetase, cytoplasmic / Q9NR19* / acyl-CoA synthetase short chain family member 2*ENSMUSG0000002760527
Acss3 / Q14DH7 / Acyl-CoA synthetase short-chain family member 3, mitochondrial / Q9H6R3* / acyl-CoA synthetase short chain family member 3*ENSMUSG0000003594824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003996 acyl-CoA ligase activity IBA
 molecular_functionGO:0004321 fatty-acyl-CoA synthase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015645 fatty acid ligase activity IBA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047760 butyrate-CoA ligase activity IEA


Pathways (from Reactome)
Pathway description
Conjugation of salicylate with glycine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001003 abnormal olfactory receptor morphology "anomalous structure of the specialized proteins within the neurons of the olfactory epithelium that normally bind and detect odorants " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

 MP:0001460 abnormal olfactory -discrimination memory "defects in the ability to exhibit a differential response to olfactory stimuli that is achieved by the reinforcement of the desired response for each particular olfactory stimulus" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

 MP:0001984 abnormal olfaction "change in the ability to smell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

 MP:0002067 abnormal sensory capabilities/reflexes/nociception "inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

 MP:0006092 abnormal olfactory neuron morphology "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950]
Show

Allelic Composition: Tyrc-a/Tyrc-a
Genetic Background: C3H/HeJ-Tyrc-a/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr