ENSMUSG00000047409


Mus musculus

Features
Gene ID: ENSMUSG00000047409
  
Biological name :Ctdspl
  
Synonyms : CTD small phosphatase-like protein / Ctdspl / P58465
  
Possible biological names infered from orthology : CTD small phosphatase like / O15194
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F3
Gene start: 118926453
Gene end: 119043998
  
Corresponding Affymetrix probe sets: 10590060 (MoGene1.0st)   1422510_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000072852
Ensembl peptide - ENSMUSP00000133755
NCBI entrez gene - 69274     See in Manteia.
MGI - MGI:1916524
RefSeq - XM_006512263
RefSeq - NM_133710
RefSeq - XM_006512262
RefSeq Peptide - NP_598471
swissprot - P58465
swissprot - G3UXN0
Ensembl - ENSMUSG00000047409
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ctdsplaENSDARG00000071673Danio rerio
 ctdsplbENSDARG00000062116Danio rerio
 CTDSPLENSGALG00000005710Gallus gallus
 CTDSPLENSG00000144677Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ctdsp1 / P58466 / Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 / Q9GZU7* / CTD small phosphatase 1*ENSMUSG0000002617666
Ctdsp2 / Q8BX07 / Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 / O14595* / CTD small phosphatase 2*ENSMUSG0000007842963
Q3TP92 / Ctdnep1 / CTD nuclear envelope phosphatase 1 / O95476*ENSMUSG0000001855931


Protein motifs (from Interpro)
Interpro ID Name
 IPR004274  FCP1 homology domain
 IPR011948  Dullard phosphatase domain, eukaryotic
 IPR023214  HAD superfamily
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001933 negative regulation of protein phosphorylation IDA
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

 MP:0010102 increased caudal vertebrae number "increased number of the bony segments of the coccyx or tail" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cpsf3tm1b(EUCOMM)Wtsi/Cpsf3tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Cpsf3tm1b(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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