ENSMUSG00000047446


Mus musculus

Features
Gene ID: ENSMUSG00000047446
  
Biological name :Arl4a
  
Synonyms : ADP-ribosylation factor-like protein 4A / Arl4a / P61213
  
Possible biological names infered from orthology : ADP ribosylation factor like GTPase 4A / P40617
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: B1
Gene start: 40005447
Gene end: 40038025
  
Corresponding Affymetrix probe sets: 10400057 (MoGene1.0st)   1425411_at (Mouse Genome 430 2.0 Array)   1431429_a_at (Mouse Genome 430 2.0 Array)   1435092_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099013
Ensembl peptide - ENSMUSP00000114458
Ensembl peptide - ENSMUSP00000122126
Ensembl peptide - ENSMUSP00000122987
NCBI entrez gene - 11861     See in Manteia.
MGI - MGI:99437
RefSeq - NM_001039515
RefSeq - NM_007487
RefSeq Peptide - NP_001034604
RefSeq Peptide - NP_031513
swissprot - G3UVX1
swissprot - P61213
Ensembl - ENSMUSG00000047446
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl4aaENSDARG00000099918Danio rerio
 ARL4AENSGALG00000027757Gallus gallus
 ARL4AENSG00000122644Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Arl4c / P61208 / ADP-ribosylation factor-like protein 4C / P56559* / ADP ribosylation factor like GTPase 4C*ENSMUSG0000004986668
Arl4d / Q99PE9 / ADP-ribosylation factor-like protein 4D / P49703* / ADP ribosylation factor like GTPase 4D*ENSMUSG0000003493660


Protein motifs (from Interpro)
Interpro ID Name
 IPR005225  Small GTP-binding protein domain
 IPR006689  Small GTPase superfamily, ARF/SAR type
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0050873 brown fat cell differentiation IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005525 GTP binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rad50tm2Jpt/Rad50tm2Jpt,Trp53tm1Tyj/Trp53tm1Tyj
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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