ENSMUSG00000047977


Mus musculus

Features
Gene ID: ENSMUSG00000047977
  
Biological name :Synb
  
Synonyms : Q8BI41 / Synb / Syncytin-B Surface protein Transmembrane protein
  
Possible biological names infered from orthology : endogenous retrovirus group FRD member 1, envelope / ERVFRD-1 / P60508
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D2
Gene start: 69289344
Gene end: 69294299
  
Corresponding Affymetrix probe sets: 10421180 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000061107
NCBI entrez gene - 239167     See in Manteia.
MGI - MGI:3045308
RefSeq - XM_006518996
RefSeq - NM_173420
RefSeq - XM_006518994
RefSeq - XM_006518995
RefSeq - XM_006518992
RefSeq Peptide - NP_775596
swissprot - Q8BI41
Ensembl - ENSMUSG00000047977
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P60508ENSG00000244476Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8BI41 / Gm27179 / Syncytin-B Surface protein Transmembrane protein / P60508* / ERVFRD-1* / endogenous retrovirus group FRD member 1, envelope*ENSMUSG00000098773100
Syna / Q5G5D5 / Syncytin-A Surface protein Transmembrane protein / P60508* / ERVFRD-1* / endogenous retrovirus group FRD member 1, envelope*ENSMUSG0000008595763
Gm14226ENSMUSG0000008489716
BC035947 / cDNA sequence BC035947ENSMUSG0000009048614


Protein motifs (from Interpro)
Interpro ID Name
 IPR018154  TLV/ENV coat polyprotein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000768 syncytium formation by plasma membrane fusion ISO
 biological_processGO:0006949 syncytium formation ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0045026 plasma membrane fusion ISO
 biological_processGO:0060716 labyrinthine layer blood vessel development IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0004201 fetal growth retardation "slow or limited development during the fetal period (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0009431 decreased fetal weight "reduced weight of a fetus compared to controls (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

 MP:0011531 abnormal syncytiotrophoblast morphology "any structural anomaly of the multi-nucleated, terminally differentiated syncytial epithelial layer of the placental villi that forms the major nutrient transport surfaces within the labyrinth layer of the rodent placenta" [ISBN-10:0521851653]
Show

Allelic Composition: Tuba1aRgsc1736/Tuba1a+
Genetic Background: C3.B6-Tuba1aRgsc1736

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr