ENSMUSG00000048373


Mus musculus

Features
Gene ID: ENSMUSG00000048373
  
Biological name :Fgfbp1
  
Synonyms : Fgfbp1 / Fibroblast growth factor-binding protein 1 / O70514
  
Possible biological names infered from orthology : Q14512
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B3
Gene start: 43978858
Gene end: 43981779
  
Corresponding Affymetrix probe sets: 10529819 (MoGene1.0st)   1419086_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056900
Ensembl peptide - ENSMUSP00000142520
Ensembl peptide - ENSMUSP00000143011
NCBI entrez gene - 14181     See in Manteia.
MGI - MGI:1096350
RefSeq - XM_006503712
RefSeq - NM_001271616
RefSeq - NM_008009
RefSeq - XM_006503711
RefSeq Peptide - NP_001258545
RefSeq Peptide - NP_032035
swissprot - O70514
Ensembl - ENSMUSG00000048373
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgfbp1bENSDARG00000091660Danio rerio
 fgfbp1bENSDARG00000039963Danio rerio
 FGFBP1ENSGALG00000014505Gallus gallus
 FGFBP1ENSG00000137440Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010510  FGF binding 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IGI
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IGI
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0017134 fibroblast growth factor binding IPI
 molecular_functionGO:0019838 growth factor binding IEA


Pathways (from Reactome)
Pathway description
FGFR2b ligand binding and activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Brpf1tm1d(EUCOMM)Wtsi/Brpf1+
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N

Allelic Composition: Fgfbp1tm1Gvdz/Fgfbp1tm1Gvdz,Tg(SOD1*G93A)1Gur/0,Tg(Thy1-YFP)16Jrs/0
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J * CBA * SJL

Allelic Composition: Fgfbp1tm1Gvdz/Fgfbp1tm1Gvdz,Tg(Thy1-YFP)16Jrs/0
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J * CBA

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Brpf1tm1d(EUCOMM)Wtsi/Brpf1+
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020327 Fgf22 / Q9ESS2 / Fibroblast growth factor 22 / Q9HCT0*  / complex / reaction
 ENSMUSG00000021732 Fgf10 / O35565 / Fibroblast growth factor 10 / O15520*  / complex / reaction
 ENSMUSG00000037225 Fgf2 / P15655 / Fibroblast growth factor 2 / P09038*  / complex / reaction
 ENSMUSG00000027208 Fgf7 / P36363 / Fibroblast growth factor 7 / P21781*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr