ENSMUSG00000048647


Mus musculus

Features
Gene ID: ENSMUSG00000048647
  
Biological name :Exd1
  
Synonyms : Exd1 / piRNA biosis protein EXD1 / Q8CDF7
  
Possible biological names infered from orthology : exonuclease 3-5 domain containing 1 / Q8NHP7
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: E5
Gene start: 119516505
Gene end: 119547627
  
Corresponding Affymetrix probe sets: 10486241 (MoGene1.0st)   1445191_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000054980
Ensembl peptide - ENSMUSP00000116082
Ensembl peptide - ENSMUSP00000126713
NCBI entrez gene - 241624     See in Manteia.
MGI - MGI:3045306
RefSeq - XM_017318165
RefSeq - NM_172857
RefSeq - XM_006499491
RefSeq - XM_006499492
RefSeq Peptide - NP_766445
swissprot - A2AQ12
swissprot - Q8CDF7
Ensembl - ENSMUSG00000048647
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 exd1ENSDARG00000098669Danio rerio
 ENSGALG00000041449Gallus gallus
 EXD1ENSG00000178997Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002562  3"-5" exonuclease domain
 IPR012337  Ribonuclease H-like superfamily
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0031047 gene silencing by RNA IMP
 biological_processGO:0034587 piRNA metabolic process IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043186 P granule ISS
 cellular_componentGO:1990923 PET complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0020362 abnormal male germ cell physiology "any functional anomaly of male germ cells whether they are undifferentiated or fully differentiated" [ORCID: orcid.org/0000-0003-4606-0597]
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Allelic Composition: Sox10Dom/Sox10+
Genetic Background: C3Fe.B6JLe-Sox10Dom

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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