ENSMUSG00000049176


Mus musculus

Features
Gene ID: ENSMUSG00000049176
  
Biological name :Frmpd4
  
Synonyms : A2AFR3 / Frmpd4 / Mus musculus FERM and PDZ domain containing 4 (Frmpd4), transcript variant 4, mRNA.
  
Possible biological names infered from orthology : FERM and PDZ domain containing 4 / Q14CM0
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F5
Gene start: 167471309
Gene end: 168577231
  
Corresponding Affymetrix probe sets: 10607888 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000107773
Ensembl peptide - ENSMUSP00000107774
Ensembl peptide - ENSMUSP00000107775
Ensembl peptide - ENSMUSP00000107777
NCBI entrez gene - 333605     See in Manteia.
MGI - MGI:3042378
RefSeq - XM_017318529
RefSeq - NM_001033330
RefSeq - NM_001290427
RefSeq - NM_001290428
RefSeq - NM_001359072
RefSeq - XM_006528889
RefSeq - XM_011247832
RefSeq - XM_011247833
RefSeq - XM_011247834
RefSeq - XM_017318528
RefSeq - XM_006528884
RefSeq - XM_006528885
RefSeq - XM_006528887
RefSeq - XM_006528888
RefSeq Peptide - NP_001028502
RefSeq Peptide - NP_001277356
RefSeq Peptide - NP_001277357
RefSeq Peptide - NP_001346001
swissprot - A2AFR3
Ensembl - ENSMUSG00000049176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tlr7ENSDARG00000075685Danio rerio
 FRMPD4ENSGALG00000033541Gallus gallus
 FRMPD4ENSG00000169933Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Frmpd3 / FERM and PDZ domain containing 3 / Q5JV73*ENSMUSG0000004242533
A2AKB4 / Frmpd1 / FERM and PDZ domain-containing protein 1 / Q5SYB0* / FERM and PDZ domain containing 1*ENSMUSG0000003561526


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR001202  WW domain
 IPR001478  PDZ domain
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035963  FERM superfamily, second domain
 IPR036020  WW domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051835 positive regulation of synapse structural plasticity ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043197 dendritic spine ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISO
 molecular_functionGO:0008289 lipid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002736 abnormal nociception after inflammation "changes in pain thresholds after inflammation" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003998 decreased thermal nociceptive threshold "a lower than average point at which thermal pain sensation is first detectable" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gabbr1tm2Bet/Gabbr1tm2Bet,Hdctm1.1(icre)Wwis/Hdc+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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