ENSMUSG00000049225


Mus musculus

Features
Gene ID: ENSMUSG00000049225
  
Biological name :Pdp1
  
Synonyms : Pdp1 / pyruvate dehyrogenase phosphatase catalytic subunit 1 / Q3UV70
  
Possible biological names infered from orthology : Q9P0J1
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A1
Gene start: 11958184
Gene end: 11966452
  
Corresponding Affymetrix probe sets: 10511580 (MoGene1.0st)   1434228_at (Mouse Genome 430 2.0 Array)   1438201_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103936
Ensembl peptide - ENSMUSP00000092766
Ensembl peptide - ENSMUSP00000103937
Ensembl peptide - ENSMUSP00000103932
Ensembl peptide - ENSMUSP00000103934
Ensembl peptide - ENSMUSP00000050521
NCBI entrez gene - 381511     See in Manteia.
MGI - MGI:2685870
RefSeq - NM_001098230
RefSeq - NM_001098231
RefSeq - NM_001290387
RefSeq - NM_001290391
RefSeq - NM_001033453
RefSeq Peptide - NP_001028625
RefSeq Peptide - NP_001091701
RefSeq Peptide - NP_001277316
RefSeq Peptide - NP_001277320
RefSeq Peptide - NP_001091700
swissprot - Q3UV70
swissprot - A8Y5Q0
swissprot - A2AJQ0
swissprot - A2AJP9
swissprot - A8Y5Q1
Ensembl - ENSMUSG00000049225
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdp1ENSDARG00000076308Danio rerio
 PDP1ENSGALG00000034876Gallus gallus
 PDP1ENSG00000164951Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pdp2 / pyruvate dehyrogenase phosphatase catalytic subunit 2 / Q9P2J9*ENSMUSG0000004837144


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR015655  Protein phosphatase 2C family
 IPR036457  PPM-type phosphatase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0035970 peptidyl-threonine dephosphorylation ISO
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity ISO
 molecular_functionGO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity ISO
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000033624 Pdpr / Q7TSQ8 / Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial / Q8NCN5* / pyruvate dehydrogenase phosphatase regulatory subunit*  / complex






 

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