ENSMUSG00000049353


Mus musculus

Features
Gene ID: ENSMUSG00000049353
  
Biological name :Rd3
  
Synonyms : Q8BRE0 / Rd3 / retinal degeneration 3
  
Possible biological names infered from orthology : Q7Z3Z2
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H6
Gene start: 191977370
Gene end: 191988283
  
Corresponding Affymetrix probe sets: 10352781 (MoGene1.0st)   1427204_at (Mouse Genome 430 2.0 Array)   1452355_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135650
Ensembl peptide - ENSMUSP00000137756
Ensembl peptide - ENSMUSP00000138049
NCBI entrez gene - 74023     See in Manteia.
MGI - MGI:1921273
RefSeq - XM_006497206
RefSeq - NM_001177900
RefSeq - NM_001303132
RefSeq - NM_023727
RefSeq - XM_006497205
RefSeq Peptide - NP_076216
RefSeq Peptide - NP_001171371
RefSeq Peptide - NP_001290061
swissprot - Q05D96
swissprot - Q8BRE0
Ensembl - ENSMUSG00000049353
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rd3ENSDARG00000031600Danio rerio
 RD3ENSGALG00000009861Gallus gallus
 RD3ENSG00000198570Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rd3l / retinal degeneration 3-like / P0DJH9*ENSMUSG0000009140227


Protein motifs (from Interpro)
Interpro ID Name
 IPR028092  Retinal degeneration protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0060041 retina development in camera-type eye IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: ApcMin/Apc+,Mmom4C57BL/6J/Mmom4FVB/NTac
Genetic Background: involves: C57BL/6J * FVB/NTac

Allelic Composition: Mrdq2BALB/cByJ/Mrdq2BALB/cByJ,Rd3rd3/Rd3rd3
Genetic Background: involves: BALB/cByJ * C57BL/6

Allelic Composition: Mrdq3C57BL/6/Mrdq3C57BL/6,Rd3rd3/Rd3rd3
Genetic Background: involves: BALB/cByJ * C57BL/6

Allelic Composition: Mrdq4C57BL/6/Mrdq4C57BL/6,Rd3rd3/Rd3rd3
Genetic Background: involves: BALB/cByJ * C57BL/6

Allelic Composition: Mrdq5C57BL/6/Mrdq5C57BL/6,Rd3rd3/Rd3rd3
Genetic Background: involves: BALB/cByJ * C57BL/6

 MP:0003728 abnormal photoreceptor layer "malformation/anomalous structure of the photoreceptor layer" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

 MP:0005551 abnormal eye electrophysiology "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

 MP:0008450 retinal photoreceptor degeneration "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

 MP:0008454 absent retinal rod cells "absence of one of the photoreceptor cell types of the vertebrate retina, in which the photopigment is in stacks of membranous disks separate from the outer cell membrane" [MESH:A08.663.650.650.670.650]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

 MP:0008515 thin retinal outer nuclear layer "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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