ENSMUSG00000049721


Mus musculus

Features
Gene ID: ENSMUSG00000049721
  
Biological name :Gal3st1
  
Synonyms : Gal3st1 / Galactosylceramide sulfotransferase / Q9JHE4
  
Possible biological names infered from orthology : galactose-3-O-sulfotransferase 1 / Q99999
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: A1
Gene start: 3983636
Gene end: 3999326
  
Corresponding Affymetrix probe sets: 10373826 (MoGene1.0st)   1454078_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058348
Ensembl peptide - ENSMUSP00000077815
Ensembl peptide - ENSMUSP00000105608
NCBI entrez gene - 53897     See in Manteia.
MGI - MGI:1858277
RefSeq - XM_006514757
RefSeq - NM_001177691
RefSeq - NM_001177703
RefSeq - NM_016922
RefSeq - XM_006514756
RefSeq Peptide - NP_058618
RefSeq Peptide - NP_001171162
RefSeq Peptide - NP_001171174
swissprot - Q9JHE4
Ensembl - ENSMUSG00000049721
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gal3st1aENSDARG00000062711Danio rerio
 gal3st1bENSDARG00000078245Danio rerio
 GAL3ST1ENSGALG00000007781Gallus gallus
 Q99999ENSG00000128242Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P61315 / Gal3st3 / Galactose-3-O-sulfotransferase 3 / Q96A11*ENSMUSG0000004765834
Gal3st4 / Mus musculus galactose-3-O-sulfotransferase 4 (Gal3st4), transcript variant 2, mRNA. / Q96RP7* / galactose-3-O-sulfotransferase 4*ENSMUSG0000007559334
Gal3st2c / Q9H3Q3* / GAL3ST2* / galactose-3-O-sulfotransferase 2*ENSMUSG0000007360832
Q6XQH0 / Gal3st2b / Galactose-3-O-sulfotransferase 2 / Q9H3Q3* / GAL3ST2*ENSMUSG0000009380532
Gal3st2 / Q9H3Q3* / galactose-3-O-sulfotransferase 2*ENSMUSG0000009465132


Protein motifs (from Interpro)
Interpro ID Name
 IPR009729  Galactose-3-O-sulfotransferase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0006682 galactosylceramide biosynthetic process IDA
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0009247 glycolipid biosynthetic process TAS
 biological_processGO:0042552 myelination IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 molecular_functionGO:0001733 galactosylceramide sulfotransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000745 tremors "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000920 abnormal myelination "atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001506 limp posture "lack of rigidity of the carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001524 impaired limb coordination "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001762 polyuria "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002685 abnormal proliferation of spermatogonia "reduction in the proliferation of the spermatogonial stem cells either due to reduced mitosis or increased apoptosis" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62271]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003492 abnormal involuntary movement "anomalies in movements that occur independent of planning (eg. reflexive behavior)" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004193 abnormal kidney papilla morphology "any structural anomaly of the apex of the renal pyramid that projects into a calyx" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005619 increased potassium excretion "greater than the normal amount of this alkaline metallic element, the most abundant intracellular ion, voided by the kidneys" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009350 decreased urine pH "increased urine acidity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010734 abnormal paranode morphology "any structural anomaly of the axon region immediately adjacent to nodes of Ranvier, where a series of cytoplasmic loops from the overlying glial cell form septate-like junctions with the axon; the axoglial junctions act as a diffusion barrier between the node and internode" [PMID:16224497]
Show

Allelic Composition: Ugt8atm1Pop/Ugt8a+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011736 decreased urine ammonia level "a reduced amount of ammonia in the urine compared to the normal state" [MGI:anna]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

Allelic Composition: Gal3st1tm1.1Hjg/Gal3st1tm1.1Hjg,Ugcgtm1Hjg/Ugcgtm1Hjg,Pax8tm1.1(cre)Mbu/Pax8+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0012551 metabolic acidosis "decreased pH and bicarbonate concentration in tissues and/or body fluids caused when the body produces too much acid or when the kidneys are not removing enough acid from the body, as in diarrhea or in kidney disease" [ISBN:0-683-40008-8]
Show

Allelic Composition: Sestd1tm1.1Bnrc/Sestd1+,Vangl2Lp/Vangl2+
Genetic Background: involves: 129S6/SvEvTac * A * C57BL/6NCr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr