ENSMUSG00000050106


Mus musculus

Features
Gene ID: ENSMUSG00000050106
  
Biological name :Tmc8
  
Synonyms : Q7TN58 / Tmc8 / Transmembrane channel-like protein 8
  
Possible biological names infered from orthology : Q8IU68 / transmembrane channel like 8
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 117782076
Gene end: 117793110
  
Corresponding Affymetrix probe sets: 10382956 (MoGene1.0st)   1458372_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115270
Ensembl peptide - ENSMUSP00000051878
Ensembl peptide - ENSMUSP00000101941
Ensembl peptide - ENSMUSP00000113570
Ensembl peptide - ENSMUSP00000113628
NCBI entrez gene - 217356     See in Manteia.
MGI - MGI:2669037
RefSeq - XM_017314497
RefSeq - NM_001195088
RefSeq - NM_001195089
RefSeq - NM_001195090
RefSeq - NM_181856
RefSeq - XM_006533123
RefSeq - XM_006533124
RefSeq - XM_017314495
RefSeq - XM_017314496
RefSeq Peptide - NP_001182017
RefSeq Peptide - NP_001182019
RefSeq Peptide - NP_862904
RefSeq Peptide - NP_001182018
swissprot - Q7TN58
swissprot - B0QZP6
swissprot - B1ATC0
swissprot - B1ATB9
swissprot - B0QZP7
Ensembl - ENSMUSG00000050106
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmc8ENSDARG00000101050Danio rerio
 TMC8ENSG00000167895Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmc7 / Q8C428 / Transmembrane channel-like protein 7 / Q7Z402* / transmembrane channel like 7*ENSMUSG0000004224630
Tmc4 / transmembrane channel like 4ENSMUSG0000001973429
Tmc3 / transmembrane channel like 3 / Q7Z5M5*ENSMUSG0000003854024
Tmc6 / Q7TN60 / transmembrane channel-like gene family 6 / Q7Z403* / transmembrane channel like 6*ENSMUSG0000002557222
Tmc2 / Q8R4P4 / Transmembrane channel-like protein 2 / Q8TDI7* / transmembrane channel like 2*ENSMUSG0000006033221
Tmc1 / Q8R4P5 / Transmembrane channel-like protein 1 / Q8TDI8* / transmembrane channel like 1*ENSMUSG0000002474920
Tmc5 / Q32NZ6 / Transmembrane channel-like protein 5 / Q6UXY8* / transmembrane channel like 5*ENSMUSG0000003065020


Protein motifs (from Interpro)
Interpro ID Name
 IPR012496  TMC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032460 negative regulation of protein oligomerization ISO
 biological_processGO:0055069 zinc ion homeostasis ISO
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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