ENSMUSG00000050197


Mus musculus

Features
Gene ID: ENSMUSG00000050197
  
Biological name :Rhox13
  
Synonyms : F6YCR7 / Homeobox protein Rhox13 / Rhox13
  
Possible biological names infered from orthology : Q8NHV9 / RHOXF1 / Rhox homeobox family member 1
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A3.3
Gene start: 38121219
Gene end: 38129967
  
Corresponding Affymetrix probe sets: 10599317 (MoGene1.0st)   1443844_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117271
NCBI entrez gene - 73614     See in Manteia.
MGI - MGI:1920864
RefSeq - NM_001185002
RefSeq Peptide - NP_001171931
swissprot - F6YCR7
Ensembl - ENSMUSG00000050197
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8NHV9ENSG00000101883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Esx1 / Q8N693* / ESX homeobox 1*ENSMUSG0000002344319
Shox2 / P70390 / short stature homeobox 2 / O60902*ENSMUSG0000002783319
Otp / O09113 / Homeobox protein orthopedia / Q5XKR4* / orthopedia homeobox*ENSMUSG0000002168517


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0071300 cellular response to retinoic acid IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002161 abnormal fertility/fecundity "reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc9a6tm1Dgen/Slc9a6+
Genetic Background: B6.129P2-Slc9a6tm1Dgen/J

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Slc9a6tm1Dgen/Slc9a6+
Genetic Background: B6.129P2-Slc9a6tm1Dgen/J

Allelic Composition: Rhox13tm1.2Chge/Y
Genetic Background: B6NCrl.129P2(Cg)-Rhox13tm1.2Chge

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc9a6tm1Dgen/Slc9a6+
Genetic Background: B6.129P2-Slc9a6tm1Dgen/J

Allelic Composition: Rhox13tm1.2Chge/Y
Genetic Background: B6NCrl.129P2(Cg)-Rhox13tm1.2Chge

 MP:0011750 abnormal seminiferous tubule epithelium morphology "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]
Show

Allelic Composition: Slc9a6tm1Dgen/Slc9a6+
Genetic Background: B6.129P2-Slc9a6tm1Dgen/J

 MP:0014052 increased male germ cell apoptosis "greater number of male germs cells that undergo programmed cell death" [MGI:csmith]
Show

Allelic Composition: Slc9a6tm1Dgen/Slc9a6+
Genetic Background: B6.129P2-Slc9a6tm1Dgen/J

Allelic Composition: Rhox13tm1.2Chge/Y
Genetic Background: B6NCrl.129P2(Cg)-Rhox13tm1.2Chge

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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