ENSMUSG00000050425


Mus musculus

Features
Gene ID: ENSMUSG00000050425
  
Biological name :Mrgprb2
  
Synonyms : Mas-related G-protein coupled receptor member B2 / Mrgprb2 / Q3KNA1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B4
Gene start: 48550965
Gene end: 48558086
  
Corresponding Affymetrix probe sets: 10563760 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000061878
NCBI entrez gene - 243979     See in Manteia.
MGI - MGI:2441674
RefSeq - NM_175531
RefSeq Peptide - NP_780740
swissprot - Q3KNA1
swissprot - W8W3G3
Ensembl - ENSMUSG00000050425
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UG61 / Mrgprb1 / Mas-related G-protein coupled receptor member B1 ENSMUSG0000007054756
Q3UG50 / Mrgprx2 / Mas-related G-protein coupled receptor member X2 ENSMUSG0000007410956
Q91ZC0 / Mrgprb4 / Mas-related G-protein coupled receptor member B4 ENSMUSG0000007055051
Q91ZC1 / Mrgprb3 / Mas-related G-protein coupled receptor member B3 ENSMUSG0000007054647
Q91ZB9 / Mrgprb5 / Mas-related G-protein coupled receptor member B5 ENSMUSG0000007055147
Mrgpra1 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000005065043
Q7TN51 / Mrgprb8 / Mas-related G-protein coupled receptor member B8 ENSMUSG0000005087043
Mrgpra9 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000007411143
Q91ZC6 / Mrgpra6 / Mus musculus MAS-related GPR, member A6 (Mrgpra6), transcript variant 1, mRNA. / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX3* / MRGPRX4* / MRGPRX1* / MRGPRX2* / MAS r...ENSMUSG0000005230341
Q8CIP3 / Mrgprx1 / Mas-related G-protein coupled receptor member X1 ENSMUSG0000007055241
Mrgpra3 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family ...ENSMUSG0000007869841
Mrgpra2a / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family...ENSMUSG0000009397341
Mrgpra2b / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MAS related GPR family member X1* / MAS related GPR family member X3* / MAS related GPR family...ENSMUSG0000009671941
Q91WW2 / Mrgpra4 / Mas-related G-protein coupled receptor member A4 / Q96LB2* / Q96LA9* / Q96LB0* / Q96LB1* / MRGPRX2* / MRGPRX3* / MRGPRX4* / MRGPRX1* / MAS related GPR family member X1* ...ENSMUSG0000006717338
Mas1 / P30554 / Proto-onco Mas / P04201* / MAS1 proto-oncogene, G protein-coupled receptor*ENSMUSG0000006803731
Mrgprd / Q91ZB8 / Mas-related G-protein coupled receptor member D / Q8TDS7* / MAS related GPR family member D*ENSMUSG0000005120730
Mrgprh / Q99MT8 / Mas-related G-protein coupled receptor member H ENSMUSG0000005940829
Mrgpre / Q91ZB7 / Mas-related G-protein coupled receptor member E / Q86SM8* / MAS related GPR family member E*ENSMUSG0000004896528
Mrgprf / Q8VCJ6 / Mas-related G-protein coupled receptor member F / Q96AM1* / MAS related GPR family member F*ENSMUSG0000003107026
Mrgprg / Q91ZB5 / Mas-related G-protein coupled receptor member G / Q86SM5* / MAS related GPR family member G*ENSMUSG0000005027624


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR026234  Mas-related G protein-coupled receptor family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cep290Gt(CC0582)Wtsi/Cep290Gt(CC0582)Wtsi
Genetic Background: 129P2/OlaHsd-Cep290Gt(CC0582)Wtsi

 MP:0008765 decreased mast cell degranulation "reduction in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell" [GO:0043303, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cep290Gt(CC0582)Wtsi/Cep290Gt(CC0582)Wtsi
Genetic Background: 129P2/OlaHsd-Cep290Gt(CC0582)Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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