ENSMUSG00000050919


Mus musculus

Features
Gene ID: ENSMUSG00000050919
  
Biological name :Zfp366
  
Synonyms : Q6NS86 / Zfp366 / zinc finger protein 366
  
Possible biological names infered from orthology : Q8N895 / ZNF366
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: D1
Gene start: 99184823
Gene end: 99250656
  
Corresponding Affymetrix probe sets: 10406859 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000060040
NCBI entrez gene - 238803     See in Manteia.
MGI - MGI:2178429
RefSeq - NM_001004149
RefSeq Peptide - NP_001004149
swissprot - Q6NS86
Ensembl - ENSMUSG00000050919
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf366ENSDARG00000040116Danio rerio
 ZNF366ENSGALG00000015008Gallus gallus
 Q8N895ENSG00000178175Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3U288 / Zfp710 / zinc finger protein 710 / Q8N1W2* / ZNF710*ENSMUSG0000004889741


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0043627 response to estrogen IEA
 cellular_componentGO:0005634 nucleus ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0030331 estrogen receptor binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000273 overriding aorta "congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

 MP:0010402 ventricular septal defect "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]
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Allelic Composition: Dnah5b2b2451Clo/Dnah5b2b2451Clo
Genetic Background: C57BL/6J-Dnah5b2b2451Clo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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