ENSMUSG00000050947


Mus musculus

Features
Gene ID: ENSMUSG00000050947
  
Biological name :Amigo1
  
Synonyms : Amigo1 / Amphoterin-induced protein 1 / Q80ZD8
  
Possible biological names infered from orthology : adhesion molecule with Ig like domain 1 / Q86WK6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.3
Gene start: 108186335
Gene end: 108192286
  
Corresponding Affymetrix probe sets: 10495270 (MoGene1.0st)   1425851_a_at (Mouse Genome 430 2.0 Array)   1427373_at (Mouse Genome 430 2.0 Array)   1444117_at (Mouse Genome 430 2.0 Array)   1447811_s_at (Mouse Genome 430 2.0 Array)   1459020_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102272
Ensembl peptide - ENSMUSP00000142852
Ensembl peptide - ENSMUSP00000061244
Ensembl peptide - ENSMUSP00000102267
Ensembl peptide - ENSMUSP00000102270
NCBI entrez gene - 229715     See in Manteia.
MGI - MGI:2653612
RefSeq - NM_001004293
RefSeq - NM_001287093
RefSeq - NM_146137
RefSeq Peptide - NP_001274022
RefSeq Peptide - NP_666249
RefSeq Peptide - NP_001004293
swissprot - Q80ZD8
swissprot - A0A0G2JEP5
swissprot - A2AE38
Ensembl - ENSMUSG00000050947
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 amigo1ENSDARG00000079620Danio rerio
 AMIGO1ENSG00000181754Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Amigo2 / Q80ZD9 / Amphoterin-induced protein 2 / Q86SJ2* / adhesion molecule with Ig like domain 2*ENSMUSG0000004821839
Amigo3 / Q8C2S7 / Amphoterin-induced protein 3 / Q86WK7* / adhesion molecule with Ig like domain 3*ENSMUSG0000003259337


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR031283  Amphoterin-induced protein
 IPR031284  Amphoterin-induced protein 1
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion ISO
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules ISS
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis ISO
 biological_processGO:0007413 axonal fasciculation ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042552 myelination ISS
 biological_processGO:0050772 positive regulation of axonogenesis ISS
 biological_processGO:0051965 positive regulation of synapse assembly IDA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1901381 positive regulation of potassium ion transmembrane transport IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032809 neuronal cell body membrane IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015459 potassium channel regulator activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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