ENSMUSG00000051050


Mus musculus

Features
Gene ID: ENSMUSG00000051050
  
Biological name :Spink14
  
Synonyms : serine peptidase inhibitor, Kazal type 14 / Spink14
  
Possible biological names infered from orthology : Q6IE38 / serine peptidase inhibitor, Kazal type 14 (putative)
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B3
Gene start: 44027869
Gene end: 44032208
  
Corresponding Affymetrix probe sets: 10455428 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000125319
Ensembl peptide - ENSMUSP00000057781
NCBI entrez gene - 433178     See in Manteia.
MGI - MGI:3646952
RefSeq - NM_001039218
RefSeq Peptide - NP_001034307
swissprot - B9EJP9
Ensembl - ENSMUSG00000051050
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6IE38ENSG00000196800Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Spink7 / serine peptidase inhibitor, Kazal type 7 (putative) / P58062*ENSMUSG0000006020127


Protein motifs (from Interpro)
Interpro ID Name
 IPR002350  Kazal domain
 IPR036058  Kazal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060046 regulation of acrosome reaction IBA
 biological_processGO:1900004 negative regulation of serine-type endopeptidase activity IBA
 cellular_componentGO:0001669 acrosomal vesicle IBA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

 MP:0013692 increased CD5-positive Ly6C-positive T cell number "increase in the number of CD5-positive T cells expressing the memory marker Ly6C" [MGI:Saran]
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Allelic Composition: Smurf2tm1b(EUCOMM)Wtsi/Smurf2tm1b(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Smurf2tm1b(EUCOMM)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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