| MP:0000126 | brittle teeth | "fragile and likely to break teeth" [J:61509] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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| MP:0002059 | abnormal seminal gland morphology | "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Dbn1tm1a(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
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| MP:0002100 | abnormal tooth morphology | "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dbn1tm1a(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
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| MP:0002818 | abnormal dentin morphology | "defects in the hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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| MP:0002819 | abnormal pulp cavity morphology | "defects in the central hollow space of a tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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| MP:0003668 | abnormal periodontal ligament morphology | "any structural anomaly in the fibrous connective tissue that surrounds the root of a tooth, separating it from and attaching it to the alveolar bone; normally extends from the base of the gingival mucosa to the fundus of the bony socket, and its main function is to hold the tooth in its socket" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66512] |
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Allelic Composition: Hrctm1.1Desa/Hrctm1.1Desa
Genetic Background: Not Specified
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| MP:0003933 | abnormal cementum morphology | "defects in the bonelike rigid connective tissue covering the root of a tooth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Hrctm1.1Desa/Hrctm1.1Desa
Genetic Background: Not Specified
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| MP:0004189 | abnormal alveolar process | "any structural anomaly of the thickened ridge of bone in the mandible and maxilla that holds the tooth sockets" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hrctm1.1Desa/Hrctm1.1Desa
Genetic Background: Not Specified
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| MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Dbn1tm1a(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
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| MP:0008528 | polycystic kidney | "the development of innumerable cysts in the kidneys filled with fluid replacing much of the mass of the kidneys leading to reduction in kidney function and frequently kidney failure" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dbn1tm1a(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1a(KOMP)Wtsi/Wtsi
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| MP:0030131 | abnormal periodontium morphology | "any structural anomaly of the specialized tissues that both surround and support the teeth, maintaining them in the maxillary and mandibular bones; it consists of four principal components: the gums (gingiva), periodontal ligament, cementum, and alveolar bone proper" [https://en.wikipedia.org/wiki/Periodontium] |
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Allelic Composition: Hrctm1.1Desa/Hrctm1.1Desa
Genetic Background: Not Specified
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| MP:0030132 | periodontium inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the periodontium (including the gums and supporting structures of the teeth)" [MGI:anna] |
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Allelic Composition: Hrctm1.1Desa/Hrctm1.1Desa
Genetic Background: Not Specified
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| MP:0030451 | abnormal dentin mineralization | "anomaly in the process by which calcium salts are deposited into dentin" [GO:0097188] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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| MP:0030466 | alveolar process atrophy | "acquired diminution of the size of the alveolar process associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030484 | abnormal osteocyte lacuna morphology | "any structural anomaly of the small cavity within the bone matrix that is occupied by an osteocyte cell body, and from which slender canaliculi radiate and penetrate the adjacent lamellae to anastomose with the canaliculi of neighboring lacunae, thus forming a system of cavities interconnected by minute canals" [https://medical-dictionary.thefreedictionary.com/osteocyte+lacuna] |
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Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030486 | abnormal osteocyte canaliculus morphology | "any structural anomaly of the slender canals situated between the lacunae of ossified bone where osteocyte cytoplasmic (dendritic) processes reside; osteocyte canaliculi are used for exchange of nutrients and waste products through gap junctions" [https://en.wikipedia.org/wiki/Bone_canaliculus, https://en.wikipedia.org/wiki/Osteocyte] |
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Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030490 | periodontal pocket | "a pathologic deepening of the gingival sulcus as a result of apical migration of the junctional epithelium and the destruction of alveolar bone and periodontal ligament fiber bundles" [https://books.google.com/books?isbn=0781784875] |
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Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030516 | abnormal junctional epithelium morphology | "any structural anomaly of the collar-like band of non-keratinized squamous epithelium that attaches the gingival soft tissue to the tooth surface; the term epithelial attachment refers to the attachment apparatus, i.e. the internal basal lamina and hemidesmosomes, that connects the junctional epithelium (JE) to the tooth surface; in the initiation of periodontitis, JE detaches from the tooth surface and converts gradually, by sprouting laterally and migrating apically, to pathological pocket epithelium" [http://dental.pitt.edu/junctional-epithelium, https://books.google.com/books?isbn=0123977630, PMID:25911094] |
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Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030517 | detached junctional epithelium | "partial or complete detachment of the junctional epithelium from the tooth surface, typically leading to periodontal pocket formation" [https://books.google.com/books?isbn=0123977630] |
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Allelic Composition: Dspptm1Kul/Dspptm1Kul
Genetic Background: B6;129-Dspptm1Kul/Mmnc
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| MP:0030543 | abnormal predentin morphology | "any structural anomaly of the initial type I collagen-rich unmineralized extracellular matrix synthesized and secreted by odontoblasts and located at the dentin-pulp interface; predentin is converted to dentin when hydroxyapatite crystals are deposited on the predentin" [https://books.google.com/books?isbn=0470958332] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Fabp1-cre)1Mmt/?
Genetic Background: involves: 129X1/SvJ
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