ENSMUSG00000053931


Mus musculus

Features
Gene ID: ENSMUSG00000053931
  
Biological name :Cnn3
  
Synonyms : Calponin-3 / Cnn3 / Q9DAW9
  
Possible biological names infered from orthology : Q15417
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: G1
Gene start: 121426497
Gene end: 121458207
  
Corresponding Affymetrix probe sets: 10495659 (MoGene1.0st)   1426724_at (Mouse Genome 430 2.0 Array)   1436759_x_at (Mouse Genome 430 2.0 Array)   1436836_x_at (Mouse Genome 430 2.0 Array)   1438354_x_at (Mouse Genome 430 2.0 Array)   1455570_x_at (Mouse Genome 430 2.0 Array)   1456380_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029773
Ensembl peptide - ENSMUSP00000143186
Ensembl peptide - ENSMUSP00000143159
Ensembl peptide - ENSMUSP00000143122
Ensembl peptide - ENSMUSP00000142526
NCBI entrez gene - 71994     See in Manteia.
MGI - MGI:1919244
RefSeq - NM_028044
RefSeq Peptide - NP_082320
swissprot - A0A0G2JDV8
swissprot - A0A0G2JFI6
swissprot - Q9DAW9
swissprot - A0A0G2JFG3
swissprot - A0A0G2JFC8
Ensembl - ENSMUSG00000053931
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnn3aENSDARG00000099510Danio rerio
 cnn3bENSDARG00000029856Danio rerio
 CNN3ENSGALG00000005597Gallus gallus
 CNN3ENSG00000117519Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cnn1 / Q08091 / Calponin-1 / P51911*ENSMUSG0000000134962
Cnn2 / Q08093 / Calponin-2 / Q99439*ENSMUSG0000000466559
Q9WVA4 / Tagln2 / Transgelin-2 / P37802*ENSMUSG0000002654727
Q9R1Q8 / Tagln3 / Transgelin-3 / Q9UI15*ENSMUSG0000002265826
Tagln / P37804 / Transgelin / Q01995*ENSMUSG0000003208525


Protein motifs (from Interpro)
Interpro ID Name
 IPR000557  Calponin repeat
 IPR001715  Calponin homology domain
 IPR001997  Calponin/LIMCH1
 IPR003096  Smooth muscle protein/calponin
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0031032 actomyosin structure organization IEA
 biological_processGO:0032780 negative regulation of ATPase activity IEA
 biological_processGO:0098609 cell-cell adhesion IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043197 dendritic spine IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0098641 cadherin binding involved in cell-cell adhesion IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0003861 abnormal nervous system development "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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