ENSMUSG00000054855


Mus musculus

Features
Gene ID: ENSMUSG00000054855
  
Biological name :Rnd1
  
Synonyms : Q8BLR7 / Rho-related GTP-binding protein Rho6 / Rnd1
  
Possible biological names infered from orthology : Q92730 / Rho family GTPase 1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F1
Gene start: 98663421
Gene end: 98677461
  
Corresponding Affymetrix probe sets: 10432236 (MoGene1.0st)   1455197_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003451
Ensembl peptide - ENSMUSP00000104777
Ensembl peptide - ENSMUSP00000113830
NCBI entrez gene - 223881     See in Manteia.
MGI - MGI:2444878
RefSeq - NM_172612
RefSeq Peptide - NP_766200
swissprot - Q8BLR7
Ensembl - ENSMUSG00000054855
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnd1aENSDARG00000030547Danio rerio
 rnd1bENSDARG00000004218Danio rerio
 RND1ENSG00000172602Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnd3 / P61588 / Rho-related GTP-binding protein RhoE / P61587* / Rho family GTPase 3*ENSMUSG0000001714462
Rnd2 / Q9QYM5 / Rho family GTPase 2 / P52198*ENSMUSG0000000131351
Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*ENSMUSG0000000223336
Rhoa / Q9QUI0 / ras homolog family member A / P61586*ENSMUSG0000000781536
4930544G11Rik / RIKEN cDNA 4930544G11 geneENSMUSG0000003646336
Rhob / P62746 / ras homolog family member B / P62745*ENSMUSG0000005436434
Rhof / Q8BYP3 / ras homolog family member F (in filopodia) / Q9HBH0* / ras homolog family member F, filopodia associated*ENSMUSG0000002944933
Rhod / P97348 / ras homolog family member D / O00212*ENSMUSG0000004184531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR003578  Small GTPase superfamily, Rho type
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization ISO
 biological_processGO:0007162 negative regulation of cell adhesion ISO
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0016322 neuron remodeling ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005912 adherens junction ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Sema4D mediated inhibition of cell attachment and migration
Sema4D induced cell migration and growth-cone collapse


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002233 Rhoc / Q62159 / Rho-related GTP-binding protein RhoC / P08134* / ras homolog family member C*  / reaction
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction
 ENSMUSG00000038387 Rras / P10833 / related RAS viral (r-ras) oncogene / P10301* / RAS related*  / reaction
 ENSMUSG00000041977 Arhgef11 / Rho guanine nucleotide exchange factor (GEF) 11 / O15085* / Rho guanine nucleotide exchange factor 11*  / complex / reaction
 ENSMUSG00000054364 Rhob / P62746 / ras homolog family member B / P62745*  / reaction
 ENSMUSG00000059495 Q8R4H2 / Arhgef12 / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA. / Q9NZN5* / Rho guanine nucleotide exchange factor 12*  / complex / reaction
 ENSMUSG00000021451 O09126 / Sema4d / Semaphorin-4D / Q92854*  / complex / reaction
 ENSMUSG00000025810 Nrp1 / P97333 / Neuropilin-1 / O14786*  / complex / reaction
 ENSMUSG00000028883 O08665 / Sema3a / Semaphorin-3A / Q14563*  / complex / reaction
 ENSMUSG00000030084 P70206 / Plxna1 / Plexin-A1 / Q9UIW2*  / complex / reaction
 ENSMUSG00000062312 Erbb2 / P70424 / Receptor tyrosine-protein kinase erbB-2 / P04626* / erb-b2 receptor tyrosine kinase 2*  / complex
 ENSMUSG00000053646 Plxnb1 / Q8CJH3 / plexin B1 / O43157*  / complex / reaction
 ENSMUSG00000009376 Met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex / reaction
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / complex / reaction
 ENSMUSG00000058230 Q91YM2 / Arhgap35 / Rho GTPase activating protein 35 / Q9NRY4*  / complex / reaction
 ENSMUSG00000053158 Fes / P16879 / Tyrosine-protein kinase Fes/Fps / P07332* / FES proto-oncogene, tyrosine kinase*  / complex / reaction






 

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