ENSMUSG00000057777


Mus musculus

Features
Gene ID: ENSMUSG00000057777
  
Biological name :Mab21l2
  
Synonyms : Mab21l2 / Protein mab-21-like 2 / Q8BPP1
  
Possible biological names infered from orthology : mab-21 like 2 / Q9Y586
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 86545581
Gene end: 86548629
  
Corresponding Affymetrix probe sets: 10499132 (MoGene1.0st)   1418934_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000076729
NCBI entrez gene - 23937     See in Manteia.
MGI - MGI:1346022
RefSeq - NM_011839
RefSeq Peptide - NP_035969
swissprot - Q8BPP1
Ensembl - ENSMUSG00000057777
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8UUZ1ENSDARG00000015266Danio rerio
 MAB21L2ENSGALG00000045289Gallus gallus
 Q9Y586ENSG00000181541Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O70299 / Mab21l1 / Putative nucleotidyltransferase MAB21L1 / Q13394* / mab-21 like 1*ENSMUSG0000005694794
Q8CI17 / Mab21l3 / Protein mab-21-like 3 / Q8N8X9* / mab-21 like 3*ENSMUSG0000004431325
Q8CEZ4 / 2310007B03Rik / Uncharacterized / Q08AI8* / C2orf54* / chromosome 2 open reading frame 54*ENSMUSG0000003415918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000772  Ricin B, lectin domain
 IPR020950  Protein male abnormal 21/21-like 2
 IPR024810  Mab-21 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010172 embryonic body morphogenesis IMP
 biological_processGO:0043010 camera-type eye development IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0003052 omphalocele "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0003078 aphakia "absence of the crystalline lens of the eye" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0003384 abnormal ventral body wall "malformation in the anterior portion of a human body or the lower surface of an animal body comprised of ectoderm and mesoderm layers that encloses the body cavity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0003425 abnormal optic vesicle formation "anomalous formation of the hollow outgrowth from the lateral aspects of the embryonic forebrain from which the retina and optic nerve develop" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94391]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0005201 abnormal retinal pigment epithelium morphology "anomaly in the epithelial layer of the retina composed of cells containing pigment granules " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0006065 abnormal heart position "the heart is displaced from the normal left-sided position and/or orientation" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0006071 abnormal retinal progenitor morphology "anomoly in the proliferation or differentiation of the cells that give rise to the various cells of the retina" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92622:]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0009725 absent lens vesicle "absence of the ectodermal invagination that forms opposite the optic cup in the primordium of the lens of the eye" [ISBN:0-12-402035-6 "Kaufman, MH The Atlas of Mouse Development", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ddb2tm1Pra/Ddb2+
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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