MP:0000716 | abnormal immune system cell morphology | "anomalous structure, development, or number of immune cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0000805 | abnormal visual cortex morphology | "malformation or absence of the area of the occipital cortex concerned with vision" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Npr1tm1(Npr1)Unc/Npr1tm1(Npr1)Unc Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002442 | abnormal leukocyte physiology | "abnormal function of any of the white blood cells (basophils, eosinophils, neutrophils, lymphocytes, or monocytes) " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0002444 | abnormal T cell physiology | "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0002459 | abnormal B cell physiology | "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0004977 | increased B-1 B cell number | "greater number of the subset of B cells found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0005154 | increased B cell proliferation | "greater than the normal response by B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0005466 | abnormal T helper 2 physiology | "anomalous response of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses; these cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions
" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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MP:0008115 | abnormal dendritic cell differentiation | "atypical production of or inability to produce a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Prkar2btm1Gsm/Prkar2btm1Gsm Genetic Background: B6.129-Prkar2btm1Gsm
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