ENSMUSG00000059327


Mus musculus

Features
Gene ID: ENSMUSG00000059327
  
Biological name :Eda
  
Synonyms : Ectodysplasin-A Ectodysplasin-A, membrane form Ectodysplasin-A, secreted form / Eda / O54693
  
Possible biological names infered from orthology : ectodysplasin A / Q92838
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: C3
Gene start: 99975606
Gene end: 100400762
  
Corresponding Affymetrix probe sets: 10600953 (MoGene1.0st)   1419596_at (Mouse Genome 430 2.0 Array)   1419597_at (Mouse Genome 430 2.0 Array)   1449524_at (Mouse Genome 430 2.0 Array)   1451877_at (Mouse Genome 430 2.0 Array)   1451925_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071397
Ensembl peptide - ENSMUSP00000109405
Ensembl peptide - ENSMUSP00000109406
Ensembl peptide - ENSMUSP00000109407
Ensembl peptide - ENSMUSP00000109408
Ensembl peptide - ENSMUSP00000109409
Ensembl peptide - ENSMUSP00000109411
Ensembl peptide - ENSMUSP00000109413
Ensembl peptide - ENSMUSP00000109410
NCBI entrez gene - 13607     See in Manteia.
MGI - MGI:1195272
RefSeq - NM_001177943
RefSeq - NM_001177937
RefSeq - NM_001177938
RefSeq - NM_001177939
RefSeq - NM_001177940
RefSeq - NM_001177941
RefSeq - NM_001177942
RefSeq - NM_001177944
RefSeq - NM_010099
RefSeq Peptide - NP_001171408
RefSeq Peptide - NP_001171409
RefSeq Peptide - NP_001171410
RefSeq Peptide - NP_001171411
RefSeq Peptide - NP_001171412
RefSeq Peptide - NP_001171413
RefSeq Peptide - NP_001171414
RefSeq Peptide - NP_001171415
RefSeq Peptide - NP_034229
swissprot - O54693
swissprot - Q1L2D6
swissprot - Q1L2D8
swissprot - Q1L2D9
swissprot - Q3UV69
Ensembl - ENSMUSG00000059327
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 edaENSDARG00000074591Danio rerio
 EDAENSGALG00000035966Gallus gallus
 EDAENSG00000158813Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006052  Tumour necrosis factor domain
 IPR008983  Tumour necrosis factor-like domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001942 hair follicle development IMP
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007160 cell-matrix adhesion IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0010467 gene expression IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0019221 cytokine-mediated signaling pathway ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0043588 skin development IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0060662 salivary gland cavitation IDA
 biological_processGO:0060789 hair follicle placode formation IGI
 biological_processGO:0061153 trachea gland development IMP
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1901222 regulation of NIK/NF-kappaB signaling ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005811 lipid droplet IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005123 death receptor binding ISS
 molecular_functionGO:0005164 tumor necrosis factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0038177 death receptor agonist activity ISS


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000116 abnormal tooth development "anomalous formation of the teeth" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: EdaTa-37H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000119 abnormal tooth eruption "anomalies in the passage of a tooth through the alveolar process and perforation of the gums" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

 MP:0000125 absent incisors "missing long pointed teeth; most anterior and prominent in the jaw" [J:17489]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0000367 abnormal coat/ hair morphology "anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/Eda+
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Y
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-23H/EdaTa-23H
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0000372 irregular coat pigmentation "uneven coloration of the hair" [J:65030]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Eda+
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Eda+
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-23H/Eda+
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0000396 increased curvature of hairs "distinct C- or S- shaped curvature of the hairs" [J:4606]
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Allelic Composition: Cblbtm1Pngr/Cblbtm1Pngr,Itktm1Litt/Itktm1Litt
Genetic Background: B6.129-Itktm1Litt Cblbtm1Pngr

Allelic Composition: EdaTa-J/Eda+
Genetic Background: 129/Sv

 MP:0000397 abnormal guard hair "anomalies of truncal hairs that contain two air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0000400 abnormal awl hair "anomalies of truncal hairs that contain two or more air cells in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0000414 alopecia "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
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Allelic Composition: Cblbtm1Pngr/Cblbtm1Pngr,Itktm1Litt/Itktm1Litt
Genetic Background: B6.129-Itktm1Litt Cblbtm1Pngr

Allelic Composition: EdaTa-J/Eda+
Genetic Background: 129/Sv

 MP:0000417 short hair "reduced average length of the hairs" [J:64948]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0000418 patchy hair "uneven spots of hair growth on the body" [J:26975]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-J/Eda+
Genetic Background: 129/Sv

 MP:0000422 delayed hair appearance "late onset of the first appearance of the fur" [J:17792]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0000440 domed skull 
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000572 abnormal autopod morphology "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0000577 absent palmar eccrine glands "missing sweat glands of the palm" [J:50311]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Y
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-23H/EdaTa-23H
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001199 thin skin "reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0001302 eyelids open at birth "widely open eyes instead of closed at perinatal stage" [J:51966]
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Allelic Composition: EdaTa-27H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0001313 increased incidence of corneal inflammation "greater than average and persistent occurrence of corneal irritation" [J:4606]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0001314 corneal opacity "complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0001340 abnormal eyelid morphology "malformation of the skin folds covering the front of the eyeball" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/Eda+
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-By/Eda+
Genetic Background: BALB/cBy

 MP:0001511 disheveled coat "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0001851 eye inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the eye" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0001852 conjunctivitis "inflammation of the mucous membrane that lines the inner surface of the eyelids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60896]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: EdaTa-43H/Eda+
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0002001 blindness "loss of the sense of sight" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0002060 abnormal skin morphology "malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0002073 abnormal hair growth "absence or reduced amount of hair or abnormal onset of hair growth cycle or development" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-33H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-26H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Y
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-23H/EdaTa-23H
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

 MP:0002074 abnormal hair texture "irregular or unusual appearance of the structure of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-33H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-26H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-By/Eda+
Genetic Background: BALB/cBy

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dsg3tm1Stan/Dsg3tm1Stan
Genetic Background: involves: 129X1/SvJ * C57BL/6J

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Eda+
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/Eda+
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-33H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-26H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Eda+
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0002095 abnormal skin pigmentation "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

Allelic Composition: EdaTa-36H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002132 abnormal respiratory system morphology "anomalous structure of pulmonary tissues " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0002163 abnormal gland morphology "abnormal development of any glandular tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0002233 abnormal nose morphology "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0002237 abnormal nasal cavity morphology "any structural anomaly of the portion of the respiratory tract that extends from the nares to the pharynx; the nasal cavity is lined with ciliated mucosa" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0002277 abnormal respiratory mucosa morphology "structural anomaly of the mucous membrane lining the respiratory tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0002576 abnormal enamel morphology "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0002689 abnormal molar morphology "structural defect of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [il:Ira Lu , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0002717 abnormal preputial gland morphology "anomalous structure of the sebaceous glands of the corona and neck of the glans penis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0002789 male pseudohermaphroditism "pseudohermaphroditism in which the gonads are male (testes) and the karyotype is XY but the secondary sex characteristics are female-like or ambiguous" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002832 coarse hair "hair shafts that are twisted or coiled and are of uneven thickness produce an overall rugged or uneven appearance and roughness to the touch" [llw2:Linda Washburn , Mouse Genome Informatics Curator, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:56826]
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Allelic Composition: EdaTa-33H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-26H/Y
Genetic Background: Not Specified

 MP:0003136 yellow coat color "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0003704 abnormal hair follicle development "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0003815 nude "having no hair at some time during or throughout lifespan, generally referring to primary genetic hairlessness" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Dscamtm1.1Pfu/Dscamtm1.1Pfu
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: EdaTa-37H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0003932 abnormal molar crown morphology "defects in the upper part of the molar, which is normally covered with enamel " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Antxr1tm1.2Lepp/Antxr1tm1.2Lepp,Antxr2tm1.2Lepp/Antxr2tm1.2Lepp
Genetic Background: involves: 129 * C57BL/6

 MP:0004381 abnormal hair follicle melanocyte morphology "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Eda+
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0004830 short incisors "reduced length of the long pointed teeth; most anterior and prominent in the jaw" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0005176 eyelids fail to open "eyes remain shut throughout life" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]
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Allelic Composition: EdaTa-37H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0005251 blepharitis "inflammation of the eyelids" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0005287 narrow eye opening "less than the normal distance from one eyelid to the other " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:71350]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0005358 abnormal incisor morphology "structural defect of the long pointed teeth; most anterior and prominent in the jaw" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85574]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0005542 corneal vascularization "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0006000 abnormal corneal epithelium "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0006236 absent meibomian glands "missing meibomian glands" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0006363 absent auchene hairs "absence of truncal hairs having a single constriction and bend about midway along the hair shaft, and contain two or more air cells in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0006365 absent guard hair "absence of the long, straight truncal hairs that contain two air cells in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

 MP:0006366 absent zigzag hairs "absence of the truncal hairs that have two or more sharp bends with diameter constrictions at the bends, and contain one air cell in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Eda+
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0006367 absent sweat gland "absence of any of the coil glands of the skin that secrete sweat" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0006369 supernumerary incisors "more than a pair, top and/or bottom, of the long pointed teeth that are the most anterior and prominent in the jaw" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0006370 abnormal phaeomelanin content "anomaly in the amount or distribution of yellow pigment in the hair" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0006371 absent phaeomelanin "yellow pigment is not present" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

 MP:0006400 decreased molar number "reduction in the number of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0006401 absent preputial gland "a lack of the sebaceous glands of the corona and neck of the glans penis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0006402 small molars "reduced size of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/Eda+,Edaraddcr/Edaradd+
Genetic Background: involves: JU/Fa

 MP:0008538 decreased zigzag hair amount "reduced number of the truncal hairs that have two or more sharp bends with diameter constrictions at the bends, and contain one air cell in the medulla" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

 MP:0009003 abnormal vibrissa number "any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0009652 abnormal palatal rugae "any structural anomaly in the transversal ridges that develop on the secondary (hard) palate" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Lef1tm1Rug/Lef1tm1Rug
Genetic Background: involves: 129S2/SvPas

Allelic Composition: EdaTa-6J/Eda+
Genetic Background: C57BL/6J Aw-J-EdaTa-6J/J

Allelic Composition: EdaTa-5J/Eda+
Genetic Background: C3H/HeJ-EdaTa-5J/J

Allelic Composition: EdaTa/Eda+
Genetic Background: C57BL/6J-Aw-J-EdaTa +/+ ArTfm/J

Allelic Composition: EdaTa/Eda+
Genetic Background: B6CBACa Aw-J/A-EdaTa/J-XO

Allelic Composition: EdaTa/Y
Genetic Background: B6CBACa Aw-J/A-EdaTa/J-XO

 MP:0009659 striated fur "hair or fur characterized by transverse, usually parallel, markings due to an anomaly in hair color, texture, or growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Eda+
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Eda+
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-32H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Eda+
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-43H/Eda+
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0009793 sebaceous gland hypertrophy "increase in the bulk size of the sebum secreting glands of the hair shaft due to cell enlargement" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0009794 sebaceous gland hyperplasia "overdevelopment and increased size of the sebum secreting glands of the hair shaft, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0010031 abnormal cranium size "deviation from the average range of cranium size compared to normal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010231 transverse fur striping "presence of stripes of pigmented hair, usually black, of variable degree and location in the coat" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/Eda+
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa-4J/Eda+
Genetic Background: involves: LDJ/LeJ

Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Eda+
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Eda+
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-33H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-32H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-26H/Eda+
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Eda+
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0010233 hairless tail "the tail is devoid of hair" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-9J/Y
Genetic Background: CBA/J

Allelic Composition: EdaTa-9J/EdaTa-9J
Genetic Background: CBA/J

Allelic Composition: EdaTa-10J/Y
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-10J/EdaTa-10J
Genetic Background: involves: C3H/HeSnJ

Allelic Composition: EdaTa-32H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Y
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-23H/EdaTa-23H
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-By/Y
Genetic Background: BALB/cBy

Allelic Composition: EdaTa-27H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-28H/Y
Genetic Background: involves: 101/H

Allelic Composition: EdaTa-35H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-37H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: EdaTa-38H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0012078 abnormal tail ring morphology "any structural anomaly of the segmentally patterned skin ridges appearing on the tail of rodents" [MGI:csmith]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-30H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-29H/Y
Genetic Background: Not Specified

Allelic Composition: EdaTa-23H/Y
Genetic Background: C3H101H-EdaTa-23H/H

Allelic Composition: EdaTa-23H/EdaTa-23H
Genetic Background: C3H101H-EdaTa-23H/H

 MP:0013177 abnormal tail tip morphology "any structural anomaly of the distal end of the tail" [MGI:anna]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

 MP:0013370 anhidrosis "complete absence of sweating in response to appropriate stimuli" [MGI:Anna]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0013373 increased sebum secretion "increased production and/or release of the lipid-rich substance that is produced by the sebaceous glands, acts to lubricate and waterproof the skin and hair of mammals, and provides antibacterial activity; sebum is released by disintegrating sebocytes that are continuously replaced from progenitors in the periphery of the sebaceous gland; its composition varies across species" [MGI:Anna]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0013378 increased sebocyte number "greater than expected number of the highly specialized, sebum-producing epithelial cells of the sebaceous glands that release their content by rupture of the cell membrane and cellular degradation" [MGI:Anna, PMID:19944183]
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Allelic Composition: EdaTa-6J/Y,Tg(MMTVtTA)1Mam/0,Tg(tetO-Eda*A1)1Dsch/0
Genetic Background: involves: C57BL/6J

 MP:0013478 corneal limbitis "inflammation of the corneal limbus" [MGI:Anna]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0013558 abnormal exocrine gland morphology "any structural anomaly of any of the glands of the exocrine system that secrete their essential product by way of a duct to some environment external to itself, either inside the body or on a surface of the body; the duct portion may be branched (compound) or unbranched (simple); the glandular portion may be tubular or acinar, or may be a mix of the two (tubuloacinar or tubuloalveolar); if the glandular portion branches, then the gland is called a branched gland Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas" [http://en.wikipedia.org/wiki/Exocrine_gland, MGI:Anna]
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Allelic Composition: EdaTa-43H/Y
Genetic Background: involves: 101/H * C3H/HeH * STOCK Myo15sh2/J

 MP:0013580 abnormal nasal gland morphology "any structural anomaly of any of the seromucous glands found in the respiratory region of the nasal mucous membrane, including anterior serous glands, seromucous glands, and Bowman glands" [http://en.wikipedia.org/wiki/Nasal_glands, MGI:Anna, UBERON:0012278]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0013582 abnormal lateral nasal gland morphology "any structural anomaly of the lateral nasal glands (the largest nasal secretory glands in rodents) which surround the maxillary sinus located in the lateral wall adjacent to each nasal passage and are characterized by cytologic features similar to those described for the major serous salivary glands; secretory contents of the LNG drain into the nasal vestibule; the LNG is a major site for the synthesis and secretion of odorant-binding proteins that serve as odorant carriers in nasal mucus; it also, synthesizes large amounts of immunoglobulin A, which is important for immune defense of the upper respiratory tract, and testosterone and salivary androgen-binding proteins, which are likely important in olfaction and reproductive behavior" [ISBN:0080454321, ISBN:0123813611, MGI:Anna]
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Allelic Composition: EdaTa/EdaTa
Genetic Background: Not Specified

Allelic Composition: EdaTa/Y
Genetic Background: Not Specified

 MP:0013745 abnormal eyelid margin morphology "any structural anomaly of the confluence of the mucosal surface of the conjunctiva, the edge of the orbicularis, and the cutaneous epithelium" [http://one.aao.org/bcscsnippetdetail.aspx?id=2b7328d7-5eb2-4df3-812a-031ff1c1f904, http://www.medilexicon.com/medicaldictionary.php?s=palpebral+margins, MGI:Anna]
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Allelic Composition: Ass1fold/Ass1fold
Genetic Background: B6Ei.P-Ass1fold/GrsrJ

 MP:0030457 abnormal molar cusp morphology "any structural anomaly of an elevation or mound on the crown of a molar tooth making up a part of the occlusal (masticatory) surface" [https://medical-dictionary.thefreedictionary.com/cusp+of+tooth, MGI:anna]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

Allelic Composition: EdaTa/EdaTa,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

Allelic Composition: EdaTa/Y,Tnfrsf19Gt(OST294987)Lex/Tnfrsf19Gt(OST294987)Lex
Genetic Background: involves: 129S5/SvEvBrd * A * C57BL/6 * CBA/CaGnLe

 MP:0030494 abnormal molar root morphology "any structural anomaly of the part of a molar tooth that is implanted in the gum" [MGI:anna]
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Allelic Composition: EdaTa/Y
Genetic Background: involves: A * C57BL * CBA * RIII

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003227 Edar / Q9R187 / Tumor necrosis factor receptor superfamily member EDAR / Q9UNE0* / ectodysplasin A receptor*  / complex / reaction
 ENSMUSG00000034457 Eda2r / Q8BX35 / Tumor necrosis factor receptor superfamily member 27 / Q9HAV5* / ectodysplasin A2 receptor*  / complex / reaction
 ENSMUSG00000095105 Edaradd / EDAR associated death domain / Q8WWZ3*  / complex / reaction






 

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