ENSMUSG00000059334


Mus musculus

Features
Gene ID: ENSMUSG00000059334
  
Biological name :Zfp36l3
  
Synonyms : Q5ISE2 / Zfp36l3 / zinc finger protein 36, C3H type-like 3
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A5
Gene start: 53774048
Gene end: 53776394
  
Corresponding Affymetrix probe sets: 10604653 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000071630
NCBI entrez gene - 333473     See in Manteia.
MGI - MGI:3525151
RefSeq - NM_001009549
RefSeq Peptide - NP_001009549
swissprot - Q5ISE2
Ensembl - ENSMUSG00000059334
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P23949 / Zfp36l2 / zinc finger protein 36, C3H type-like 2 / P47974* / ZFP36 ring finger protein like 2*ENSMUSG0000004581719
P23950 / Zfp36l1 / zinc finger protein 36, C3H type-like 1 / Q07352* / ZFP36 ring finger protein like 1*ENSMUSG0000002112715
Zfp36 / P22893 / zinc finger protein 36 / ZFP36 ring finger protein*ENSMUSG0000004478614


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR011004  Trimeric LpxA-like superfamily
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IDA
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IDA
 molecular_functionGO:0003730 mRNA 3"-UTR binding IBA
 molecular_functionGO:0017091 AU-rich element binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001770 abnormal iron level "anomalous concentrations of this metallic element that normally occurs in the heme of hemoglobin, myoglobin, transferrin, ferritin, and iron-containing porphyrins; it is an essential component of enzymes such as catalase, peroxidase, and various cytochromes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
Genetic Background: C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp

Allelic Composition: Zfp36l3tm1Pjb/Y
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0003123 paternal imprinting "specific loci are inactivated during spermatogenesis and are not expressed in offspring " [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator, llw2:Linda Washburn, Mouse Genome Informatics Curator]
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Allelic Composition: Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
Genetic Background: C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
Genetic Background: C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp

Allelic Composition: Zfp36l3tm1Pjb/Zfp36l3+
Genetic Background: involves: C57BL/6 * C57BL/6NTac

Allelic Composition: Zfp36l3tm1Pjb/Y
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0009615 abnormal zinc homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of zinc that normally is a cofactor in many proteins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
Genetic Background: C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp

Allelic Composition: Zfp36l3tm1Pjb/Y
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0010382 abnormal dosage compensation, by inactivation of X chromosome "anomaly in the process of compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex" [GO:0009048]
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Allelic Composition: Zfp36l3tm1Pjb/Zfp36l3+
Genetic Background: involves: C57BL/6 * C57BL/6NTac

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Mpzl3tm1(KOMP)Mbp/Mpzl3tm1(KOMP)Mbp
Genetic Background: C57BL/6-Tyrc-Brd Mpzl3tm1(KOMP)Mbp

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Zfp36l3tm1Pjb/Y
Genetic Background: involves: C57BL/6 * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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