ENSMUSG00000059395


Mus musculus

Features
Gene ID: ENSMUSG00000059395
  
Biological name :Nkapl
  
Synonyms : Nkapl / NKAP-like protein / Q5SZT7
  
Possible biological names infered from orthology : NFKB activating protein like / Q5M9Q1
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A3.1
Gene start: 21467047
Gene end: 21468509
  
Corresponding Affymetrix probe sets: 10408037 (MoGene1.0st)   1449561_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000065168
NCBI entrez gene - 66707     See in Manteia.
MGI - MGI:1913957
RefSeq - NM_025719
RefSeq Peptide - NP_079995
swissprot - Q5SZT7
Ensembl - ENSMUSG00000059395
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkapENSDARG00000033450Danio rerio
 NKAPENSGALG00000020262Gallus gallus
 NKAPLENSG00000189134Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nkap / Q9D0F4 / NF-kappa-B-activating protein / Q8N5F7* / NFKB activating protein*ENSMUSG0000001640962


Protein motifs (from Interpro)
Interpro ID Name
 IPR009269  NF-kappa-B-activating protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003682 chromatin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Vhltm1Wml/Vhl+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Vhltm1Wml/Vhl+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Vhltm1Wml/Vhl+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Vhltm1Wml/Vhl+
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0014052 increased male germ cell apoptosis "greater number of male germs cells that undergo programmed cell death" [MGI:csmith]
Show

Allelic Composition: Vhltm1Wml/Vhl+
Genetic Background: involves: 129S4/SvJae * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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