ENSMUSG00000060747


Mus musculus

Features
Gene ID: ENSMUSG00000060747
  
Biological name :Ifnl3
  
Synonyms : Ifnl3 / Interferon lambda-3 / Q8CGK6
  
Possible biological names infered from orthology : IFNL2 / interferon lambda 2 / Q8IZI9 / Q8IZJ0
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 28522836
Gene end: 28524322
  
Corresponding Affymetrix probe sets: 10551526 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000077473
NCBI entrez gene - 338374     See in Manteia.
MGI - MGI:2450574
RefSeq - NM_177396
RefSeq - XM_006540130
RefSeq Peptide - NP_796370
swissprot - Q8CGK6
Ensembl - ENSMUSG00000060747
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 B4ER10ENSGALG00000033141Gallus gallus
 IFNL2ENSG00000183709Homo sapiens
 IFNL3ENSG00000197110Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifnl2 / Q4VK74 / Interferon lambda-2 / IFNL3* / Q8IZJ0* / Q8IZI9* / interferon lambda 3*ENSMUSG0000005912893


Protein motifs (from Interpro)
Interpro ID Name
 IPR029177  Interferon lambda


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007259 JAK-STAT cascade IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0045071 negative regulation of viral genome replication ISS
 biological_processGO:0045087 innate immune response IDA
 biological_processGO:0050778 positive regulation of immune response IEA
 biological_processGO:0050863 regulation of T cell activation IBA
 biological_processGO:0051607 defense response to virus IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005125 cytokine activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000032175 Tyk2 / tyrosine kinase 2 / P29597*  / complex
 ENSMUSG00000062157 Ifnlr1 / Q8CGK5 / Interferon lambda receptor 1 / Q8IU57*  / complex
 ENSMUSG00000028530 Jak1 / Janus kinase 1 / P23458*  / complex






 

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