ENSMUSG00000061165


Mus musculus

Features
Gene ID: ENSMUSG00000061165
  
Biological name :Olfr160
  
Synonyms : olfactory receptor family 8 subfamily A member 1 / Olfr160
  
Possible biological names infered from orthology : OR8A1 / Q8NGG7
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A4
Gene start: 37708964
Gene end: 37716250
  
Corresponding Affymetrix probe sets: 10592362 (MoGene1.0st)   1422381_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100468
Ensembl peptide - ENSMUSP00000148600
Ensembl peptide - ENSMUSP00000151178
NCBI entrez gene - 80706     See in Manteia.
MGI - MGI:1931271
RefSeq - NM_030553
RefSeq Peptide - NP_085030
swissprot - Q8VGE3
Ensembl - ENSMUSG00000061165
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000026595Gallus gallus
 OLFR3BENSGALG00000034019Gallus gallus
 OLFR6ENSGALG00000026035Gallus gallus
 OR8U1ENSGALG00000041386Gallus gallus
 OR8A1ENSG00000196119Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Olfr985 / olfactory receptor family 8 subfamily D member 4 / OR8D4* / Q8NGM9*ENSMUSG0000004907366
Olfr924 / OR8D2* / Q9GZM6* / olfactory receptor family 8 subfamily D member 2 (gene/pseudogene)*ENSMUSG0000006210364
Olfr926 / OR8D2* / Q9GZM6* / olfactory receptor family 8 subfamily D member 2 (gene/pseudogene)*ENSMUSG0000006433364
Olfr26 / OR8D1* / Q8WZ84* / olfactory receptor family 8 subfamily D member 1*ENSMUSG0000004766761
Olfr974ENSMUSG0000005149361
Olfr933 / OR8D1* / Q8WZ84* / olfactory receptor family 8 subfamily D member 1*ENSMUSG0000005851561
Olfr930 / OR8D1* / Q8WZ84* / olfactory receptor family 8 subfamily D member 1*ENSMUSG0000006322161


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000725  Olfactory receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISA
 biological_processGO:0007411 axon guidance IGI
 biological_processGO:0007608 sensory perception of smell ISA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004984 olfactory receptor activity ISA
 molecular_functionGO:0005549 odorant binding IBA


Pathways (from Reactome)
Pathway description
Olfactory Signaling Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000819 abnormal olfactory bulb morphology "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461]
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Allelic Composition: Olfr151tm11(Olfr160)Mom/Olfr151+,Olfr160tm1(Olfr151)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Olfr151tm1Mom/Olfr151+,Olfr160tm1(Olfr151)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Olfr151tm2Mom/Olfr151+,Olfr160tm6Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Olfr151tm10Mom/Olfr151+,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Adcy3tm1Drs/Adcy3tm1Drs,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

Allelic Composition: Cnga2tm1Mom/Cnga2tm1Mom,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cnga2tm1Mom/Y,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Olfr151tm25Mom/?,Olfr160tm6Mom/?,Pcdhatm3Tyag/Pcdhatm3Tyag
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv

 MP:0000968 abnormal sensory neuron innervation "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]
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Allelic Composition: Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+
Genetic Background: involves: C57BL/6J * CBA/J

 MP:0001983 abnormal olfactory system physiology "abnormal function of the system relating to smell " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cnga2tm1Mom/Cnga2tm1Mom,Olfr160tm5(Cnga2)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cnga2tm1Mom/Y,Olfr160tm5(Cnga2)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0001984 abnormal olfaction "change in the ability to smell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myf5tm3(cre)Sor/Myf5tm3(cre)Sor,Myod1tm1Jae/Myod1tm1Jae
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: ApcMin/Apc+,Tgfbr1tm1Bopa/Tgfbr1+
Genetic Background: B6.Cg-Tgfbr1tm1Bopa ApcMin

Allelic Composition: Olfr160tm1.1(COP4*/EYFP)Tboz/Olfr160tm1.1(COP4*/EYFP)Tboz
Genetic Background: involves: 129 * C57BL/6

 MP:0002184 abnormal innervation "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Myf5tm3(cre)Sor/Myf5tm3(cre)Sor,Myod1tm1Jae/Myod1tm1Jae
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002739 abnormal olfactory bulb development "abnormality in the progression of the formation of the olfactory bulb" [J:65380, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Myf5tm3(cre)Sor/Myf5tm3(cre)Sor,Myod1tm1Jae/Myod1tm1Jae
Genetic Background: involves: 129S4/SvJae * C57BL/6J

Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

 MP:0002882 abnormal neuron "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Myf5tm3(cre)Sor/Myf5tm3(cre)Sor,Myod1tm1Jae/Myod1tm1Jae
Genetic Background: involves: 129S4/SvJae * C57BL/6J

 MP:0002961 abnormal axon guidance "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Ccdc88atm3.1Mat/Ccdc88atm3.1Mat
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Cnga2tm1Mom/Cnga2tm1Mom,Olfr160tm5(Cnga2)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cnga2tm1Mom/Y,Olfr160tm5(Cnga2)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0005236 abnormal olfactory nerve morphology "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Adcy3tm1Drs/Adcy3tm1Drs,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

 MP:0006092 abnormal olfactory neuron morphology "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950]
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Allelic Composition: Ebf2tm1Reed/Ebf2+,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Allelic Composition: Cnga2tm1Mom/Cnga2tm1Mom,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Cnga2tm1Mom/Y,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

Allelic Composition: Ebf2tm3.1(Zfp423*)Reed/Ebf2+,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/10J

 MP:0009450 abnormal axon fasiculation "anomaly in the process by which axons form into bundles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccdc88atm3.1Mat/Ccdc88atm3.1Mat
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0009946 abnormal olfactory bulb layer morphology "any structural anomaly of the laminar structure of the forebrain region that coordinates neuronal signaling involved in the perception of smell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

 MP:0009948 abnormal olfactory bulb glomerular layer morphology 
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Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

 MP:0010057 abnormal olfactory bulb outer nerve layer moprhology "any strucutral anomaly of the outerpost layer of the olfactory bulb; consists primarily of olfactory afferent axons and ensheathing glia" [PMID:12533617]
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Allelic Composition: Hcn1tm2Kndl/Hcn1tm2Kndl,Olfr160tm6Mom/Olfr160tm6Mom
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J

 MP:0012014 abnormal olfactory neuron innervation pattern "any changes in the placement, morphology or number of axons from olfactory neurons to an effector tissue or to olfactory glomeruli or olfactory bulb" [MGI:csmith]
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Allelic Composition: Olfr151tm1Mom/Olfr151+,Olfr160tm1(Olfr151)Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Olfr151tm2Mom/Olfr151+,Olfr160tm6Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Olfr151tm10Mom/Olfr151+,Olfr160tm4Mom/Olfr160+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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