ENSMUSG00000061414


Mus musculus

Features
Gene ID: ENSMUSG00000061414
  
Biological name :Cracr2a
  
Synonyms : Cracr2a / EF-hand calcium-binding domain-containing protein 4B / Q3UP38
  
Possible biological names infered from orthology : calcium release activated channel regulator 2A / Q9BSW2
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: F3
Gene start: 127561338
Gene end: 127674248
  
Corresponding Affymetrix probe sets: 10542050 (MoGene1.0st)   10542060 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000071494
Ensembl peptide - ENSMUSP00000148569
NCBI entrez gene - 381812     See in Manteia.
MGI - MGI:2685919
RefSeq - XM_011241400
RefSeq - NM_001033464
RefSeq - XM_006506346
RefSeq - XM_006506350
RefSeq - XM_006506351
RefSeq - XM_006506341
RefSeq - XM_006506343
RefSeq - XM_006506344
RefSeq - XM_006506345
RefSeq Peptide - NP_001028636
swissprot - Q3UP38
swissprot - A0A1D5RLZ8
Ensembl - ENSMUSG00000061414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CRACR2AENSDARG00000068231Danio rerio
 cracr2abENSDARG00000045758Danio rerio
 Q9BSW2ENSG00000130038Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80ZJ8 / Cracr2b / EF-hand calcium-binding domain-containing protein 4A / Q8N4Y2* / calcium release activated channel regulator 2B*ENSMUSG0000004820029


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR002048  EF-hand domain
 IPR005225  Small GTP-binding protein domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002115 store-operated calcium entry ISO
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0032237 activation of store-operated calcium channel activity ISO
 biological_processGO:0051928 positive regulation of calcium ion transport ISO
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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