ENSMUSG00000061923


Mus musculus

Features
Gene ID: ENSMUSG00000061923
  
Biological name :Odf1
  
Synonyms : Odf1 / outer dense fiber of sperm tails 1
  
Possible biological names infered from orthology : Q14990
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: B3.1
Gene start: 38219203
Gene end: 38226735
  
Corresponding Affymetrix probe sets: 10423798 (MoGene1.0st)   1422585_at (Mouse Genome 430 2.0 Array)   1440821_x_at (Mouse Genome 430 2.0 Array)   1457659_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080632
NCBI entrez gene - 18285     See in Manteia.
MGI - MGI:97424
RefSeq - NM_008757
RefSeq Peptide - NP_032783
swissprot - A6H656
Ensembl - ENSMUSG00000061923
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ODF1ENSGALG00000035199Gallus gallus
 ODF1ENSG00000155087Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002068  Alpha crystallin/Hsp20 domain
 IPR008978  HSP20-like chaperone
 IPR037552  Outer dense fibre protein 1, alpha crystallin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0001520 outer dense fiber IEA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

Allelic Composition: Odf1tm1Shf/Odf1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0008893 detached sperm flagellum "fragmentation of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility from the sperm head" [MESH:A05.360.490.890.840, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0009238 coiled sperm flagellum "abnormal twisting of the sperm flagellum into coils or spirals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0009831 abnormal sperm midpiece morphology "any structural abnormality of the highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece" [PMID:14581499]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

 MP:0009832 abnormal sperm mitochondrial sheath morphology "any structural anomaly or impairment of the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum" [PMID:14581499]
Show

Allelic Composition: Sox5tm1.1Tlu/Sox5tm1.1Tlu
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * FVB/N) or (involves: 129S1/Sv * 129X1/SvJ * CD-1 * FVB/N)

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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