ENSMUSG00000062778


Mus musculus

Features
Gene ID: ENSMUSG00000062778
  
Biological name :Chia1
  
Synonyms : Acidic mammalian chitinase / Chia1 / Q91XA9
  
Possible biological names infered from orthology : CHIA / chitinase, acidic / Q9BZP6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 106113229
Gene end: 106132120
  
Corresponding Affymetrix probe sets: 10495136 (MoGene1.0st)   1416456_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000121967
Ensembl peptide - ENSMUSP00000078134
NCBI entrez gene - 81600     See in Manteia.
MGI - MGI:1932052
RefSeq - NM_023186
RefSeq Peptide - NP_075675
swissprot - D3Z1S6
swissprot - Q91XA9
Ensembl - ENSMUSG00000062778
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000003519Gallus gallus
 ENSGALG00000031807Gallus gallus
 CHIAENSGALG00000023760Gallus gallus
 CHIAENSG00000134216Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Chil5 / chitinase-like 5 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000004387360
Chil3 / O35744 / Chitinase-like protein 3 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000004080956
Chil4 / Q91Z98 / Chitinase-like protein 4 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000006377955
Chil6 / chitinase-like 6 / CHIA* / Q9BZP6* / chitinase, acidic*ENSMUSG0000002790254
Chit1 / Q9D7Q1 / Chitotriosidase-1 / Q13231* / chitinase 1*ENSMUSG0000002645048
Ovgp1 / Q62010 / Oviduct-specific glycoprotein / Q12889* / oviductal glycoprotein 1*ENSMUSG0000007434046
Chil1 / Q61362 / Chitinase-3-like protein 1 / CHI3L1* / P36222* / chitinase 3 like 1*ENSMUSG0000006424638


Protein motifs (from Interpro)
Interpro ID Name
 IPR001223  Glycoside hydrolase family 18, catalytic domain
 IPR001579  Glycoside hydrolase, chitinase active site
 IPR002557  Chitin binding domain
 IPR011583  Chitinase II
 IPR017853  Glycoside hydrolase superfamily
 IPR029070  Chitinase insertion domain superfamily
 IPR036508  Chitin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000272 polysaccharide catabolic process IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002532 production of molecular mediator involved in inflammatory response ISO
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006030 chitin metabolic process IEA
 biological_processGO:0006032 chitin catabolic process ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0090197 positive regulation of chemokine secretion ISS
 cellular_componentGO:0005576 extracellular region IBA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004568 chitinase activity ISO
 molecular_functionGO:0008061 chitin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0019900 kinase binding ISO


Pathways (from Reactome)
Pathway description
Digestion of dietary carbohydrate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Chd7tm2a(EUCOMM)Wtsi/Chd7+
Genetic Background: 129S5;B6N-Chd7tm2a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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