ENSMUSG00000063234


Mus musculus

Features
Gene ID: ENSMUSG00000063234
  
Biological name :Gpr84
  
Synonyms : Gpr84 / G protein-coupled receptor 84
  
Possible biological names infered from orthology : Q9NQS5
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: F3
Gene start: 103308235
Gene end: 103310612
  
Corresponding Affymetrix probe sets: 10433101 (MoGene1.0st)   1420591_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078753
NCBI entrez gene - 80910     See in Manteia.
MGI - MGI:1934129
RefSeq - NM_030720
RefSeq - XM_006521554
RefSeq Peptide - NP_109645
swissprot - A0A0R4J100
Ensembl - ENSMUSG00000063234
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr84ENSDARG00000077308Danio rerio
 GPR84ENSG00000139572Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005466 abnormal T helper 2 physiology "anomalous response of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses; these cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Shank3tm1.1Geno/Shank3tm1.1Geno
Genetic Background: involves: C57BL/6

 MP:0008672 increased interleukin-13 secretion "increase in the production or release of a cytokine synthesized by T-cells that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-cells, and appears to play a role in regulating inflammatory and immune responses" [MESH:D12.644.276.374.465.513]
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Allelic Composition: Shank3tm1.1Geno/Shank3tm1.1Geno
Genetic Background: involves: C57BL/6

 MP:0008699 increased interleukin-4 secretion "increase in the production or release of a soluble factor produced by activated T-cells that induces the expression of MHC class II genes and FC receptors on B-cells and causes their proliferation and differentiation; it also acts on T-cells, mast cells and several other hematopoietic lineage cells" [MESH:D12.644.276.374.465.504]
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Allelic Composition: Shank3tm1.1Geno/Shank3tm1.1Geno
Genetic Background: involves: C57BL/6

 MP:0008702 increased interleukin-5 secretion "increase in the production or release of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells" [MESH:D12.644.276.374.465.505]
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Allelic Composition: Shank3tm1.1Geno/Shank3tm1.1Geno
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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