ENSMUSG00000065479


Mus musculus

Features
Gene ID: ENSMUSG00000065479
  
Biological name :Mir125a
  
Synonyms : microRNA 125a / Mir125a
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: A3.2
Gene start: 17830812
Gene end: 17830879
  
Corresponding Affymetrix probe sets: 10442085 (MoGene1.0st)   
  
Cross references: MGI - MGI:2676809
Ensembl - ENSMUSG00000065479
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010629 negative regulation of gene expression IDA
 biological_processGO:0035278 miRNA mediated inhibition of translation IDA
 biological_processGO:1903671 negative regulation of sprouting angiogenesis IDA
 molecular_functionGO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004799 increased susceptibility to experimental autoimmune encephalomyelitis "greater likelihood that an organism will develop disease symptoms similar to human multiple sclerosis upon induction with antigens to Myelin Basic Protein (MBP), Proteolipid Protein (PLP), and/or Myelin Oligodendrocyte glycoprotein (MOG)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brinp1tm1.1Pib/Brinp1tm1.1Pib
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0004946 abnormal regulatory T cell physiology "any functional anomaly of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or "Tregs") and other T cell types that have suppressor function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brinp1tm1.1Pib/Brinp1tm1.1Pib
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0004974 decreased regulatory T cell number "reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Brinp1tm1.1Pib/Brinp1tm1.1Pib
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0008566 increased interferon-gamma secretion "increase in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Brinp1tm1.1Pib/Brinp1tm1.1Pib
Genetic Background: involves: BALB/cJ * C57BL/6

 MP:0008681 increased interleukin-17 secretion "increase in the production or release of a proinflammatory cytokine produced primarily by T-cells or their precursors" [MESH:D12.644.276.374.465.517]
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Allelic Composition: Brinp1tm1.1Pib/Brinp1tm1.1Pib
Genetic Background: involves: BALB/cJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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