ENSMUSG00000066129


Mus musculus

Features
Gene ID: ENSMUSG00000066129
  
Biological name :Kndc1
  
Synonyms : Kndc1 / Protein very KIND / Q0KK55
  
Possible biological names infered from orthology : kinase non-catalytic C-lobe domain containing 1 / Q76NI1
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F4
Gene start: 139894696
Gene end: 139941537
  
Corresponding Affymetrix probe sets: 10558548 (MoGene1.0st)   1428599_at (Mouse Genome 430 2.0 Array)   1458209_at (Mouse Genome 430 2.0 Array)   1458411_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113856
Ensembl peptide - ENSMUSP00000050586
NCBI entrez gene - 76484     See in Manteia.
MGI - MGI:1923734
RefSeq - NM_177261
RefSeq Peptide - NP_796235
swissprot - D3Z3X0
swissprot - Q0KK55
Ensembl - ENSMUSG00000066129
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FP102122.1ENSDARG00000116483Danio rerio
 ENSGALG00000007007Gallus gallus
 KNDC1ENSG00000171798Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000651  Ras-like guanine nucleotide exchange factor, N-terminal
 IPR001895  Ras guanine-nucleotide exchange factors catalytic domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011019  KIND domain
 IPR023578  Ras guanine nucleotide exchange factor domain superfamily
 IPR029899  Kinase non-catalytic C-lobe domain-containing protein 1
 IPR036964  Ras guanine-nucleotide exchange factor catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0007264 small GTPase mediated signal transduction IEA
 biological_processGO:0021707 cerebellar granule cell differentiation IMP
 biological_processGO:0048814 regulation of dendrite morphogenesis IDA
 biological_processGO:0050773 regulation of dendrite development IDA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032045 guanyl-nucleotide exchange factor complex IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043204 perikaryon IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005088 Ras guanyl-nucleotide exchange factor activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Esx1tm1Bhr/Esx1+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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