ENSMUSG00000069476


Mus musculus

Features
Gene ID: ENSMUSG00000069476
  
Biological name :Zfp616
  
Synonyms : Zfp616 / zinc finger protein 616
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B4
Gene start: 74069955
Gene end: 74087292
  
Corresponding Affymetrix probe sets: 10378420 (MoGene1.0st)   1438875_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112245
Ensembl peptide - ENSMUSP00000136549
Ensembl peptide - ENSMUSP00000074365
Ensembl peptide - ENSMUSP00000104103
NCBI entrez gene - 327963     See in Manteia.
MGI - MGI:3650906
RefSeq - NM_001177570
RefSeq Peptide - NP_001171041
swissprot - A7DTG8
swissprot - J3QN14
swissprot - Q5SVV3
Ensembl - ENSMUSG00000069476
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm29106ENSMUSG0000010203041
Zfp808 / zinc finger protein 80ENSMUSG0000007486735
Gm13212ENSMUSG0000007850235
Zfp729a / zinc finger protein 729a / ZNF99* / A6NN14* / A8MXY4* / ZNF729* / zinc finger protein 99* / zinc finger protein 729*ENSMUSG0000002151034
Gm4924ENSMUSG0000007342734
Zfp62 / Q8C827 / zinc finger protein 62 / Q8NB50* / ZFP62 zinc finger protein*ENSMUSG0000004631133
Zfp27 / P10077 / zinc finger protein 27 / Q6P3V2* / Q52M93* / ZNF585A* / ZNF585B* / zinc finger protein 585A* / zinc finger protein 585B*ENSMUSG0000006204033
5430403G16Rik / RIKEN cDNA 5430403G16 geneENSMUSG0000007276333
BC024063 / cDNA sequence BC024063ENSMUSG0000011216032
Zfp442 / zinc finger protein 442ENSMUSG0000006813031
Gm14124ENSMUSG0000007900831
Zfp160 / zinc finger protein 160 / Q9HCG1* / Q96SE7* / ZNF160* / ZNF347* / zinc finger protein 347*ENSMUSG0000006794230
Zfp873 / zinc finger protein 873ENSMUSG0000006137129
Zfp788 / zinc finger protein 788 / Q9H0M5* / ZNF700* / zinc finger protein 700*ENSMUSG0000007416528


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0008124 decreased plasmacytoid dendritic cell number "reduced number of phagocytic dendritic cells that are morphologically similar to plasma cells, but do not express B lineage markers, and produce large amounts of alpha/beta interferons (IFN-/) in response to viral and bacterial stimuli" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:15596797]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0008126 increased dendritic cell number "greater number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0013023 decreased Ly6C high monocyte number "decrease in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues" [MGI:Annie_Speak]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0013775 increased KLRG1-positive T-helper cell number "increase in the number of CD4-positive alpha-beta T-helper cells expressing KLRG1, a marker associated with activation" [MGI:Saran]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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