ENSMUSG00000069825


Mus musculus

Features
Gene ID: ENSMUSG00000069825
  
Biological name :Spata22
  
Synonyms : Spata22 / spermatogenesis associated 22
  
Possible biological names infered from orthology : Q8NHS9
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B4
Gene start: 73329741
Gene end: 73355913
  
Corresponding Affymetrix probe sets: 10378385 (MoGene1.0st)   10378395 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000113799
MGI - MGI:2685728
MGI - MGI:6121532
swissprot - B0QZP0
Ensembl - ENSMUSG00000069825
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spata22ENSDARG00000098537Danio rerio
 SPATA22ENSGALG00000040395Gallus gallus
 Q8NHS9ENSG00000141255Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5SV06 / Spata22 / Spermatosis-associated protein 22 / Q8NHS9* / spermatogenesis associated 22*ENSMUSG0000011292099


Protein motifs (from Interpro)
Interpro ID Name
 IPR033536  Spermatogenesis-associated protein 22


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000711 meiotic DNA repair synthesis IEA
 biological_processGO:0007129 synapsis IEA
 biological_processGO:0007276 gamete generation IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Spata22tm1b(KOMP)Wtsi/Spata22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Spata22tm1b(KOMP)Wtsi/Ucd

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0001131 abnormal ovarian follicles "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

Allelic Composition: Spata22tm1b(KOMP)Wtsi/Spata22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Spata22tm1b(KOMP)Wtsi/Ucd

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

Allelic Composition: Spata22tm1b(KOMP)Wtsi/Spata22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Spata22tm1b(KOMP)Wtsi/Ucd

 MP:0002016 ovarian cysts "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0004805 absent oocytes "absence of mature germ cells in the female" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

 MP:0010124 decreased bone mineral content "reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Spata22tm1b(KOMP)Wtsi/Spata22tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Spata22tm1b(KOMP)Wtsi/Ucd

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Kat2atm3.1Roth/Kat2atm3.2Roth,Tg(Pcp2-cre)2Mpin/0
Genetic Background: involves: 129

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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