ENSMUSG00000071317


Mus musculus

Features
Gene ID: ENSMUSG00000071317
  
Biological name :Bves
  
Synonyms : Blood vessel epicardial substance / Bves / Q9ES83
  
Possible biological names infered from orthology : Q8NE79
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B2
Gene start: 45335772
Gene end: 45372479
  
Corresponding Affymetrix probe sets: 10362968 (MoGene1.0st)   1419003_at (Mouse Genome 430 2.0 Array)   1439848_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093382
NCBI entrez gene - 23828     See in Manteia.
MGI - MGI:1346013
RefSeq - XM_006512737
RefSeq - NM_024285
RefSeq - XM_006512736
RefSeq Peptide - NP_077247
swissprot - Q9ES83
Ensembl - ENSMUSG00000071317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bvesENSDARG00000058548Danio rerio
 BVESENSGALG00000015410Gallus gallus
 BVESENSG00000112276Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Popdc2 / Q9ES82 / Popeye domain-containing protein 2 / Q9HBU9* / popeye domain containing 2*ENSMUSG0000002280324
Popdc3 / Q9ES81 / Popeye domain-containing protein 3 / Q9HBV1* / popeye domain containing 3*ENSMUSG0000001984823


Protein motifs (from Interpro)
Interpro ID Name
 IPR006916  Popeye protein
 IPR014710  RmlC-like jelly roll fold
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001921 positive regulation of receptor recycling IDA
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IGI
 biological_processGO:0002931 response to ischemia IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0007519 skeletal muscle tissue development IEA
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0016192 vesicle-mediated transport IDA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IDA
 biological_processGO:0040017 positive regulation of locomotion IDA
 biological_processGO:0042391 regulation of membrane potential IGI
 biological_processGO:0043087 regulation of GTPase activity IDA
 biological_processGO:0048278 vesicle docking IMP
 biological_processGO:0060931 sinoatrial node cell development IMP
 biological_processGO:0060973 cell migration involved in heart development IMP
 biological_processGO:0090136 epithelial cell-cell adhesion IEA
 biological_processGO:2001135 regulation of endocytic recycling IMP
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0016328 lateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0031253 cell projection membrane IDA
 cellular_componentGO:0042383 sarcolemma ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030552 cAMP binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004115 abnormal sinoatrial node morphology "structural anomaly in the small mass of modified cardiac muscle fibers located at the junction of the superior vena cava and the right atruim that is the source of contraction impulses for the heart" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: Swiss

 MP:0004484 altered response of heart to induced stress "change in the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: Swiss

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0006142 abnormal sinoatrial node conduction "anomaly in the generation or transfer of electrical impulses that trigger contraction of the atria and ventricles" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: Swiss

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Bach2tm1a(EUCOMM)Wtsi/Bach2tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Bach2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0010637 sinus bradycardia "a type of decreased heart rhythm in which fewer than the normal number of impulses arise from the sinoatrial (SA) node" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: Swiss

 MP:0013239 impaired skeletal muscle regeneration "reduced ability to repair skeletal muscle after injury or disease" [MGI:csmith]
Show

Allelic Composition: Pax6Sey/Pax6Sey
Genetic Background: involves: Swiss

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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